Evidence map›Paper›PMID 33293111›Full record

ArticleUltrasound in medicine & biology2021

Ultrahigh-Frequency Echocardiography of Autonomic Devoid Phox2B Homozygous Embryos Does Not Reveal a Significant Cardiac Phenotype before Embryo Death.

Deepa Mokshagundam, William Kowalski, Iris Garcia-Pak, Brenda Klaunberg, Joseph Nam, Yoh-Suke Mukouyama, Linda Leatherbury

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ultrasound in medicine & biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Sympathetic Neurons Regulate Cardiomyocyte Maturation in Culture.Frontiers in cell and developmental biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Deepa MokshagundamLaboratory of Stem Cell and Neuro-Vascular Biology, Cell and Developmental Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA; Division of Pediatric Cardiology, Children's National Hospital, Washington, DC, USA.
William KowalskiLaboratory of Stem Cell and Neuro-Vascular Biology, Cell and Developmental Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Iris Garcia-PakLaboratory of Stem Cell and Neuro-Vascular Biology, Cell and Developmental Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Brenda KlaunbergNIH Mouse Imaging Facility, National Institutes of Health, Bethesda, Maryland, USA.
Joseph NamLaboratory of Stem Cell and Neuro-Vascular Biology, Cell and Developmental Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Yoh-Suke MukouyamaLaboratory of Stem Cell and Neuro-Vascular Biology, Cell and Developmental Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Linda LeatherburyLaboratory of Stem Cell and Neuro-Vascular Biology, Cell and Developmental Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA; Division of Pediatric Cardiology, Children's National Hospital, Washington, DC, USA. Electronic address: lleather@childrensnational.org.
National Institutes of Health · USNational Heart Lung and Blood Institute · USChildren's National · US

Funding

The study of neuro-vascular interactions in the developing heartZIAHL006116 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI MUKOUYAMA, YOH-SUKE · 2011 to 2025
$9.4M
Intramural NIH HHS ZIA HL006116
6 · The paper itself

Abstract

In vivo micro-imaging of mice is useful in studying the genetic basis of cardiac development in mutant embryos. We examined Phox2b

Indexed as

AnimalsEchocardiographyEmbryo LossHeartHomeodomain ProteinsHomozygoteMiceMice, Inbred C57BLPhenotypeTranscription FactorsHomeodomain ProteinsPhox2b protein, mouseTranscription FactorsCardiac developmentEchocardiographyFetal echocardiographyMurine fetal echocardiographyPhox2bUltrahigh-frequency ultrasoundVisualSonics Vevo 2100

Identifiers

PMID33293111
PMCPMC8520219
OpenAlexW3110866995

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.