Evidence map›Paper›PMID 33292873›Full record

Trial reportActa neuropsychiatrica2021

Adjunctive yoga training for persons with schizophrenia: who benefits?

Triptish Bhatia, Swathi Gujral, Vikas Sharma, Nupur Kumari, Joel Wood, Maribeth A Wesesky, Jacquelynn Jones, Louanne W Davis, Satish Iyenger, Gretchen L Haas and 2 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Acta neuropsychiatrica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Triptish Bhatia *Indo-USA Projects and NCU-ICMR, Department of Psychiatry and De-addiction, Centre of Excellence in Mental Health, ABVIMS. -Dr. R.M.L. Hospital, New Delhi, India.
Swathi Gujral *VA VISN 4 Mental Illness Research, Education, and Clinical Center of Excellence (MIRECC), VA Pittsburgh Healthcare System, Pittsburgh, PA, USA.
Vikas SharmaNCU-ICMR, Department of Psychiatry and De-addiction, Centre of Excellence in Mental Health, ABVIMS. -Dr.R.M.L. Hospital, New Delhi, India.
Nupur KumariSATYAM-DST Project, Department of Psychiatry and De-addiction, Centre of Excellence in Mental Health, ABVIMS. -Dr.R.M.L. Hospital, New Delhi, India.
Joel WoodWestern Psychiatric Hospital, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Maribeth A WeseskyWestern Psychiatric Hospital, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Jacquelynn JonesWestern Psychiatric Hospital, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Louanne W DavisDepartment of Research, Roudebush VA Medical Center, Indiana University School of Medicine, Indianapolis, IN, USA.
Satish IyengerDepartment of Statistics, University of Pittsburgh, Pittsburgh, PA, USA.
Gretchen L HaasVA VISN 4 Mental Illness Research, Education, and Clinical Center of Excellence (MIRECC), VA Pittsburgh Healthcare System, Pittsburgh, PA, USA.
Vishwajit L NimgaonkarWestern Psychiatric Hospital, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Smita N DeshpandeDepartment of Psychiatry and De-addiction, Centre of Excellence in Mental Health, ABVIMS. -Dr.R.M.L. Hospital, New Delhi, India.ORCID https://orcid.org/0000-0001-7770-9657
University of Pittsburgh · USMental Illness Research, Education and Clinical Centers · USRichard L. Roudebush VA Medical Center · US

Funding

Psychiatric research infrastructure for intervention and implementation in India – TEAMSD43TW009114 · FIC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Smita N Deshpande, Mary Elizabeth Hawk · 2014 to 2026
$3.2M
Aerobic Exercise for Optimizing Cognitive and Brain Health In Remitted Late-Life DepressionK23MH125074 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GUJRAL, SWATHI · 2021 to 2025
$828k
FIC NIH HHS D43 TW009114NIMH NIH HHS K23 MH125074
6 · The paper itself

Abstract

objectiveThe aim of this study was to identify factors associated with acceptability and efficacy of yoga training (YT) for improving cognitive dysfunction in individuals with schizophrenia (SZ).

methodsWe analysed data from two published clinical trials of YT for cognitive dysfunction among Indians with SZ: (1) a 21-day randomised controlled trial (RCT, N = 286), 3 and 6 months follow-up and (2) a 21-day open trial (n = 62). Multivariate analyses were conducted to examine the association of baseline characteristics (age, sex, socio-economic status, educational status, duration, and severity of illness) with improvement in cognition (i.e. attention and face memory) following YT. Factors associated with acceptability were identified by comparing baseline demographic variables between screened and enrolled participants as well as completers versus non-completers.

resultsEnrolled participants were younger than screened persons who declined participation (t = 2.952, p = 0.003). No other characteristics were associated with study enrollment or completion. Regarding efficacy, schooling duration was nominally associated with greater and sustained cognitive improvement on a measure of facial memory. No other baseline characteristics were associated with efficacy of YT in the open trial, the RCT, or the combined samples (n = 148).

conclusionsYT is acceptable even among younger individuals with SZ. It also enhances specific cognitive functions, regardless of individual differences in selected psychosocial characteristics. Thus, yoga could be incorporated as adjunctive therapy for patients with SZ. Importantly, our results suggest cognitive dysfunction is remediable in persons with SZ across the age spectrum.

Indexed as

AdultAttentionCase-Control StudiesCognitionCognitive DysfunctionFemaleFollow-Up StudiesHumansIndiaMaleMiddle AgedMultivariate AnalysisNeuropsychological TestsPatient Acceptance of Health CareRetrospective StudiesSchizophreniaattentioncognitionface memoryschizophreniayoga

Identifiers

PMID33292873
PMCPMC8113063
OpenAlexW3111033339

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.