Evidence map›Paper›PMID 33292781›Full record

ArticleInternational journal of retina and vitreous2020

Autoimmune retinopathy: findings and limitations from optical coherence tomography angiography.

Joseph Raevis, Tyler Etheridge, Spencer Cleland, Mihai Mititelu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of retina and vitreous, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Joseph RaevisDepartment of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 206 University Ave 2870, Madison, WI, USA. Raevis@wisc.edu.ORCID http://orcid.org/0000-0003-3274-4154
Tyler EtheridgeDepartment of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 206 University Ave 2870, Madison, WI, USA.
Spencer ClelandDepartment of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 206 University Ave 2870, Madison, WI, USA.
Mihai MititeluDepartment of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 206 University Ave 2870, Madison, WI, USA.
University of Wisconsin–Madison · US

Funding

UW Vision Research Core - Administrative CoreP30EY016665 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI Donna M Peters · 2005 to 2026
$12.6M
NEI NIH HHS P30 EY016665
6 · The paper itself

Abstract

BACKGROUND AND

objectiveTo report novel findings and limitations from optical coherence tomography angiography (OCTA) in the evaluation of autoimmune retinopathy (AIR). STUDY

designWe retrospectively reviewed features of five patients diagnosed with AIR and five controls. OCTA scans were obtained and manually segmented to provide accurate measurements of foveal avascular zone (FAZ), vessel density, and retinal thickness at different levels.

resultsThe total retina and superficial vessel density throughout the whole scan were similar between AIR and controls (p = 0.14 and p = 0.11), whereas deep vessel density was decreased in AIR compared controls (p = 0.02). Decreased vessel density was most pronounced in the parafoveal and perifoveal areas (p = 0.01 and p = 0.01). AIR patients also had reduction of total retinal thickness in the perifoveal zone (p = 0.03), corresponding to outer retinal thinning (p = 0.001).

conclusionThis small series shows that AIR patients have reduced deep vessel density, particularly in the parafoveal and perifoveal regions and a decrease in macular thickness. These findings show correlation with the classic "flying saucer" sign seen on OCT.

Indexed as

Autoimmune retinopathyCancer associated retinopathyfoveal avascular zoneMelanoma associated retinopathyOCTAOptical coherence tomography angiographyretinal thicknessvessel density

Identifiers

PMID33292781
PMCPMC7713440
OpenAlexW3109547923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.