ArticleInternational journal of retina and vitreous2020
Vascular density of optic nerve head in diabetic retinopathy using optical coherence tomography angiography.
Article in International journal of retina and vitreous, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- Macular, Peripapillary, and Midperipheral Nonperfusion in Diabetic Subjects: A Wide-Field OCTA Quantification.Translational vision science & technology · 2026Article
- The Effect of Periodontitis Severity on Diabetic Retinopathy: An Optical Coherence Tomography Study.Diagnostics (Basel, Switzerland) · 2026Article
- Effect of Refractive Status on Peripapillary Retinal Nerve Fiber Layer Thickness and Vascular Density: A Prospective Optical Coherence Tomography Angiography-Based Study.Medical journal of the Islamic Republic of Iran · 2025Article
- Effect of panretinal photocoagulation versus intravitreal bevacizumab injection on optic disc microcirculation in patients with diabetic retinopathy.International journal of retina and vitreous · 2024Article
- Colorimetric Analyses of the Optic Nerve Head and Retina Indicate Increased Blood Flow After Vitrectomy.Translational vision science & technology · 2024Article
- The Robust Lamina Cribrosa Vasculature: Perfusion and Oxygenation Under Elevated Intraocular Pressure.Investigative ophthalmology & visual science · 2024Article
- Transient but not chronic hyperglycemia accelerates ocular glymphatic transport.Fluids and barriers of the CNS · 2024Article
- Upregulation of PCED1B-AS1 in proliferative diabetic retinopathy and its involvement in retinal vascular endothelial cell proliferation.BMC ophthalmology · 2022Article
- Optic nerve head perfusion changes in eyes with proliferative diabetic retinopathy treated with intravitreal ranibizumab or photocoagulation: a randomized controlled trial.Medical hypothesis, discovery & innovation ophthalmology journal · 2022Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo measure optic nerve head (ONH) blood perfusion using optical coherence tomography angiography (OCTA) at various stages of diabetic retinopathy (DR).
methodsOne hundred seventy six eyes of 94 patients included in this retrospective single-centre cross-sectional study. The subjects were studied in normal, no diabetic retinopathy (NDR), non-proliferative diabetic retinopathy (NPDR) and proliferative retinopathy (PDR) groups. The eyes were subjected to AngioDisc ONH imaging using OCTA for papillary (Disc) and peripapillary (RPC) vascular density (VD) evaluation.
resultsThe mean age of the participants was 56.08 ± 8.87 years and 34 (36.2 percent) were male. With increased DR severity, a statistically significant decrease in peripapillary VD was found. The study showed that only VD of the whole RPC (W-RPC) could be a valid biomarker in the staging assessment. VD of RPC, in all subsections, was considerably different from normal cases in the PDR group. Visual acuity was correlated with whole image ONH VD. The duration of DM, FBS, hyperlipidemia and DME had no effect on the ONH perfusion.
conclusionsThe study showed that only the W-RPC VD could be a reasonable marker in the staging assessment. VDs assessed by OCTA can be useful for assessing and tracking early ONH changes in DR patients.
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