Evidence map›Paper›PMID 33292692›Full record

ArticleZoological letters2020

The role of clockwork orange in the circadian clock of the cricket Gryllus bimaculatus.

Yasuaki Tomiyama, Tsugumichi Shinohara, Mirai Matsuka, Tetsuya Bando, Taro Mito, Kenji Tomioka

Open access · goldAbstract read
In one paragraph

Article in Zoological letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yasuaki TomiyamaGraduate School of Natural Science and Technology, Okayama University, Okayama, 700-8530, Japan.
Tsugumichi ShinoharaGraduate School of Natural Science and Technology, Okayama University, Okayama, 700-8530, Japan.
Mirai MatsukaGraduate School of Natural Science and Technology, Okayama University, Okayama, 700-8530, Japan.
Tetsuya BandoGraduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University, Okayama, 700-8558, Japan.
Taro MitoGraduate School of Technology, Industrial and Social Sciences, Tokushima University, Tokushima, 770-8513, Japan.
Kenji TomiokaGraduate School of Natural Science and Technology, Okayama University, Okayama, 700-8530, Japan. tomioka@cc.okayama-u.ac.jp.ORCID http://orcid.org/0000-0001-7951-8950
Okayama University · JPOkayama University of Science · JPTokushima University · JP

Funding

Japan Society for the Promotion of Science JP18H02480Japan Society for the Promotion of Science London JP15H04400
6 · The paper itself

Abstract

The circadian clock generates rhythms of approximately 24 h through periodic expression of the clock genes. In insects, the major clock genes period (per) and timeless (tim) are rhythmically expressed upon their transactivation by CLOCK/CYCLE, with peak levels in the early night. In Drosophila, clockwork orange (cwo) is known to inhibit the transcription of per and tim during the daytime to enhance the amplitude of the rhythm, but its function in other insects is largely unknown. In this study, we investigated the role of cwo in the clock mechanism of the cricket Gryllus bimaculatus. The results of quantitative RT-PCR showed that under a light/dark (LD) cycle, cwo is rhythmically expressed in the optic lobe (lamina-medulla complex) and peaks during the night. When cwo was knocked down via RNA interference (RNAi), some crickets lost their locomotor rhythm, while others maintained a rhythm but exhibited a longer free-running period under constant darkness (DD). In cwo

Indexed as

Circadian clockClock geneClockwork orangeCricketcry2Locomotor rhythmMolecular oscillation

Identifiers

PMID33292692
PMCPMC7659126
OpenAlexW3099517003

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.