Evidence map›Paper›PMID 33292690›Full record

ArticleJournal of eating disorders2020

Echocardiographic abnormalities in 124 severely malnourished adult anorexia nervosa patients: frequency and relationship with body composition and biological features.

Mouna Hanachi, Annabel Pleple, Caroline Barry, Marika Dicembre, Emilie Latour, Maeva Duquesnoy, Jean-Claude Melchior, Abdallah Fayssoil

Open access · goldAbstract read
In one paragraph

Article in Journal of eating disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Mouna HanachiClinical Nutrition Unit, Raymond Poincaré Hospital (AP-HP), Garches, France. mouna.hanachi@aphp.fr.ORCID http://orcid.org/0000-0002-7228-8723
Annabel PlepleClinical Nutrition Unit, Raymond Poincaré Hospital (AP-HP), Garches, France.
Caroline BarryFrance INSERM, U1178, Paris, VI, France.
Marika DicembreClinical Nutrition Unit, Raymond Poincaré Hospital (AP-HP), Garches, France.
Emilie LatourClinical Nutrition Unit, Raymond Poincaré Hospital (AP-HP), Garches, France.
Maeva DuquesnoyClinical Nutrition Unit, Raymond Poincaré Hospital (AP-HP), Garches, France.
Jean-Claude MelchiorClinical Nutrition Unit, Raymond Poincaré Hospital (AP-HP), Garches, France.
Abdallah FayssoilInstitut de Myologie, Groupe Hospitalier Pitié-Salpêtrière, APHP, Paris, France.
Assistance Publique – Hôpitaux de Paris · FRInserm · FRSorbonne Université · FRUniversité de Versailles Saint-Quentin-en-Yvelines · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnorexia Nervosa (AN) is a complex psychiatric disorder that can lead to specific somatic complications. Heart abnormalities are frequently reported, while their frequency and associated factors in severely malnourished AN patients remain poorly defined.

objectivesThis study aimed to characterize echocardiographic abnormalities in severely malnourished AN patients and to assess associated clinical, biological and related body composition features.

methodsBetween January 2013 and January 2015, all severely malnourished adult patients with AN (Mental Disorders, 4th Edn.-DSM IVr) were included in a monocentric study performed in in a highly specialized AN inpatient unit. Electrocardiogram (ECG) and echocardiography were used to assess both heart rhythm and function. All inpatients underwent a Doppler echocardiography procedure after undergoing combined blood volume adjustment, micronutrients deficiencies supplementation and electrolyte disorders correction. Right Ventricular (RV) and Left Ventricular (LV) systolic and diastolic functions were collected and compared to 29 healthy normal subjects in a control group.

resultsOne hundred and 24 patients (119 (96%) women, 5 (4%) men) with a mean age of 30.1 ± 11 years old and an average Body Mass Index (BMI) of 12 kg/m

conclusionHeart abnormalities are frequent in malnourished patients with AN, particularly in AN-BP type. Both liver enzymes and body composition abnormalities tended to be associated with heart dysfunction (non-significant association). Prospective studies are needed to better characterize and describe the evolution of cardiac abnormalities during the refeeding period and subsequent weight restoration.

Indexed as

Anorexia nervosaBody compositionEchocardiographyHeart abnormalitiesMalnutrition

Identifiers

PMID33292690
PMCPMC7661163
OpenAlexW3100108029

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.