Evidence map›Paper›PMID 33292676›Full record

ArticleCardio-oncology (London, England)2020

Aerobic and resistance exercise improves Reynolds risk score in overweight or obese breast cancer survivors.

Kyuwan Lee, Nathalie Sami, Debu Tripathy, Wendy Demark-Wahnefried, Mary K Norris, Kerry S Courneya, Christina M Dieli-Conwright

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardio-oncology (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01140282 (Combined Exercise Program for Early Breast Cancer Survivors), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01140282 nacompletednot on this map

Combined Exercise Program for Early Breast Cancer Survivors

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2012 to 2018Enrolled106ConditionsStage I Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast CancerArmsquestionnaire administration, quality-of-life assessment, management of therapy complications, exercise intervention
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Impact of exercise on physical health status in bladder cancer patients.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2023
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Kyuwan LeeDepartment of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA, 91010, USA.
Nathalie SamiDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.
Debu TripathyDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Wendy Demark-WahnefriedDepartment of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Mary K NorrisDivision of Population Sciences, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, 375 Longwood Avenue, Boston, MA, 02215, USA.
Kerry S CourneyaFaculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Alberta, T6G 2H9, Canada.
Christina M Dieli-ConwrightDivision of Population Sciences, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, 375 Longwood Avenue, Boston, MA, 02215, USA. ChristinaM_Dieli-Conwright@DFCI.Harvard.edu.ORCID http://orcid.org/0000-0001-9093-7259
Harvard University · USCity of Hope · USThe University of Texas MD Anderson Cancer Center · USUniversity of Alabama at Birmingham · USUniversity of Alberta · CAUniversity of Southern California · US

Funding

Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2000 to 2026
$31.9M
Metabolic Syndrome and Breast Cancer: Effects of a Combined Exercise InterventionK07CA160718 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI DIELI-CONWRIGHT, CHRISTINA · 2011 to 2015
$629k
NCI NIH HHS K07CA160718NIDDK NIH HHS P30 DK056336
6 · The paper itself

Abstract

backgroundBreast cancer survivors have double the risk of mortality from cardiovascular disease than age-matched women without a cancer history. Reynolds risk score (RRS) is a validated algorithm for the assessment of cardiovascular disease risk. This secondary analysis sought to examine the effects of a 16-week aerobic and resistance exercise intervention on RRS in overweight or obese breast cancer survivors. METHODS AND

resultsOne hundred overweight or obese (BMI > 25 kg/m

conclusionA 16-week aerobic and resistance exercise intervention is an effective approach to reduce the risk of cardiovascular disease in breast cancer survivors. Exercise during cancer survivorship should be considered to reduce the risk for cardiovascular disease risk in overweight women breast cancer survivors.

trial registrationClinicalTrials.gov: NCT01140282 . Registered 9 June 2010.

Indexed as

CancerCardiovascular diseaseExercise

Identifiers

PMID33292676
PMCPMC7684890
OpenAlexW3107365314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.