Evidence map›Paper›PMID 33292652›Full record

ReviewBiomarker research2020

N6-methyladenine modification in noncoding RNAs and its function in cancer.

Xinyu Yang, Xiang Hu, Jinting Liu, Ruiqing Wang, Chen Zhang, Fengjiao Han, Yuhong Chen, Daoxin Ma

Open access · goldAbstract readReview
In one paragraph

Review in Biomarker research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 56 citations in OpenAlex.

  1. The multifaceted role of 3-methyladenine in cancer therapy.Journal of physiology and biochemistry · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. NImmunity, inflammation and disease · 2024
    Review
  6. Article
  7. ExploringHorticulture research · 2024
    Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Decoding the regulatory roles of non-coding RNAs in cellular metabolism and disease.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Review
  14. Review
  15. Review
  16. mCell death & disease · 2022
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xinyu YangDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong, P.R. China.
Xiang HuDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong, P.R. China.
Jinting LiuDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong, P.R. China.
Ruiqing WangDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong, P.R. China.
Chen ZhangDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong, P.R. China.
Fengjiao HanDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong, P.R. China.
Yuhong ChenDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong, P.R. China.
Daoxin MaDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong, P.R. China. daoxinma@sdu.edu.cn.
Qilu Hospital of Shandong University · CN

Funding

National Natural Science Foundation of China No. 81873439National Natural Science Foundation of China No. 91642110
6 · The paper itself

Abstract

Non-coding RNAs are the main component of the extensive transcription results of the mammalian genome. They are not transcribed into proteins but play critical roles in regulating multiple biological processes and affecting cancer progression. m6A modification is one of the most abundant internal RNA modification of mammalian cells, and it involves almost all aspects of RNA metabolism. Recent research revealed tight correlations between m6A modification and ncRNAs and indicated the interaction between m6A and ncRNAs act a pivotal part in the development of cancer. The correlation between m6A modification and ncRNAs provides a new perspective for exploring the potential regulatory mechanism of tumor gene expression, and suggest that m6A modification and ncRNAs may be important prognostic markers and therapeutic targets for multiple cancers. In this review, we summarize the potential regulatory mechanisms between m6A methylation and ncRNAs, highlighting how their relationship affects biological functions in cancer.

Indexed as

Cancerm6A modificationNoncoding RNAs

Identifiers

PMID33292652
PMCPMC7653994
OpenAlexW3105678703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.