Evidence map›Paper›PMID 33292595›Full record

ArticleCell & bioscience2020

DNA methylation modification is associated with gonadal differentiation in Monopterus albus.

Xin Wang, Fengling Lai, Jun Xiong, Wang Zhu, Bifeng Yuan, Hanhua Cheng, Rongjia Zhou

Open access · goldAbstract read
In one paragraph

Article in Cell & bioscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  5. Molecular Characterization and Expression ofAnimals : an open access journal from MDPI · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xin WangHubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, 430072, China.
Fengling LaiHubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, 430072, China.
Jun XiongKey Laboratory of Analytical Chemistry for Biology and Medicine of Ministry of Education, Department of Chemistry, Wuhan University, Wuhan, 430072, China.
Wang ZhuHubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, 430072, China.
Bifeng YuanKey Laboratory of Analytical Chemistry for Biology and Medicine of Ministry of Education, Department of Chemistry, Wuhan University, Wuhan, 430072, China.
Hanhua ChengHubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, 430072, China. hhcheng@whu.edu.cn.
Rongjia ZhouHubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, 430072, China. rjzhou@whu.edu.cn.ORCID http://orcid.org/0000-0002-9701-8009
Wuhan University · CN

Funding

National Natural Science Foundation of China 31771370National Natural Science Foundation of China 31771487National Natural Science Foundation of China 31970539
6 · The paper itself

Abstract

backgroundBoth testis and ovary can be produced sequentially in an individual with the same genome when sex reversal occurs in the teleost Monopterus albus, and epigenetic modification is supposed to be involved in gonadal differentiation. However, DNA methylation regulation mechanism underlying the gonadal differentiation remains unclear.

resultsHere, we used liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) to simultaneously determine endogenous levels of both 5-methyl-2'-deoxycytidine (m

conclusionsThese data suggested that dynamic change of DNA methylation modification is associated with gonadal differentiation.

Indexed as

DNA methylationGonadPromoterVertebrates

Identifiers

PMID33292595
PMCPMC7654577
OpenAlexW3102591654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.