ReviewJournal of animal science and biotechnology2020
Advances in fatty acids nutrition in dairy cows: from gut to cells and effects on performance.
Review in Journal of animal science and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
82 citing papers in PubMed, 1 synthesis or guideline pooled it, 168 citations in OpenAlex.
- Effect of Dietary Vegetable Sources Rich in Unsaturated Fatty Acids on Milk Production, Composition, and Cheese Fatty Acid Profile in Sheep: A Meta-Analysis.Frontiers in veterinary science · 2021Pooled it
- Optimizing concentrate feeding and calcium-fatty acid supplementation for sustainable milk production in Indonesian smallholder dairy farms.Tropical animal health and production · 2026Article
- Effect of dietary inclusion of rumen-protected flaxseed oil (Linum usitatissimum) on intake, ingestive behavior, diet particle selectivity, digestibility, nitrogen balance, and blood parameters of lambs.Tropical animal health and production · 2026Article
- Precision dietary strategies for enriching animal-derived foods with antioxidants and omega-3 fatty acids.Veterinary and animal science · 2026Review
- Enhancing lactation performance and energy utilisation efficiency through dietary inclusion of apple pomace silage and hempseed cake in dairy cows.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Changes in the nutritive quality, fatty acid and terpenoid profile of milk and "Plaisentif" cheese from nine Italian Alpine dairy farms during two grazing seasons.Italian journal of food safety · 2026Article
- Effects of Precision Dietary Protein Reduction on Lactational Performance, Milk Fatty Acid Profile, and Antioxidant Status in Mid-Lactation Dairy Cows.Animals : an open access journal from MDPI · 2026Article
- Effects of Prepartum Supplementation with Flaxseed and Black Soldier Fly Larvae Oils on Fatty Acid Composition and Lipid Quality Indices in Sheep Milk.Molecules (Basel, Switzerland) · 2026Article
- Effects of lipid supplementation on milk fatty acid profile of lactating cows under semi-confined summer conditions in southern Brazil.Tropical animal health and production · 2026Article
- Effects of an Essential Oil Blend on In Vitro Methane Production, In Vitro and In Vivo Nutrient Digestibility, Growth Performance, and Meat Quality in Lithuanian Blackface Lambs.Animals : an open access journal from MDPI · 2026Article
- Rumen Microbiome Development in Lambs Following Maternal and Early-Life Prebiotic Mannan-Rich Fraction (MRF) Supplementation.Animals : an open access journal from MDPI · 2026Article
- Herbal remedies for hepatic diseases: A review of medicinal herbs in the treatment of liver disorders.Chinese herbal medicines · 2026Review
- Investigating the potential role of propionylcarnitine in milk pentadecanoic acid synthesis in Chinese holstein dairy cows using multi-omics analysis.BMC genomics · 2026Article
- Immunometabolic-uterine-ovarian interactions and flushing therapy in dairy cows: a narrative review.Veterinary world · 2026Review
- Negative Energy Balance in Transition Cows Induces Complex Changes in Lipid Profile of Milk.Metabolites · 2026Article
- Regional variations of lipids in camel milk from Xinjiang, China: a UHPLC-MS/MS-based lipidomics study.Frontiers in veterinary science · 2026Article
- Plasma Metabolomics Reveals Systemic Metabolic Remodeling in Early-Lactation Dairy Cows Fed aToxins · 2025Article
- Dietary modulation of the rumen microbiome drives the expression of metabolic and methanogenic pathways inmSphere · 2025Article
- Intramammary lipopolysaccharide infusion alters the fatty acid composition of blood lipid fractions but not milk in dairy cows.Journal of animal science and biotechnology · 2025Article
- Bioclimatic Influence on the Nutritional Composition, In Vitro Ruminal Fermentation Dynamics, and Greenhouse Gas Emissions ofAnimals : an open access journal from MDPI · 2025Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High producing dairy cows generally receive in the diet up to 5-6% of fat. This is a relatively low amount of fat in the diet compared to diets in monogastrics; however, dietary fat is important for dairy cows as demonstrated by the benefits of supplementing cows with various fatty acids (FA). Several FA are highly bioactive, especially by affecting the transcriptome; thus, they have nutrigenomic effects. In the present review, we provide an up-to-date understanding of the utilization of FA by dairy cows including the main processes affecting FA in the rumen, molecular aspects of the absorption of FA by the gut, synthesis, secretion, and utilization of chylomicrons; uptake and metabolism of FA by peripheral tissues, with a main emphasis on the liver, and main transcription factors regulated by FA. Most of the advances in FA utilization by rumen microorganisms and intestinal absorption of FA in dairy cows were made before the end of the last century with little information generated afterwards. However, large advances on the molecular aspects of intestinal absorption and cellular uptake of FA were made on monogastric species in the last 20 years. We provide a model of FA utilization in dairy cows by using information generated in monogastrics and enriching it with data produced in dairy cows. We also reviewed the latest studies on the effects of dietary FA on milk yield, milk fatty acid composition, reproduction, and health in dairy cows. The reviewed data revealed a complex picture with the FA being active in each step of the way, starting from influencing rumen microbiota, regulating intestinal absorption, and affecting cellular uptake and utilization by peripheral tissues, making prediction on in vivo nutrigenomic effects of FA challenging.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.