Evidence map›Paper›PMID 33292288›Full record

ReviewCost effectiveness and resource allocation : C/E2020

A systematic review of the budget impact analyses for antitumor drugs of lung cancer.

Lu Han, Xin Zhang, Wen-Qi Fu, Cheng-Yao Sun, Xian-Ming Zhao, Liang-Ru Zhou, Guo-Xiang Liu

Abstract readReview
In one paragraph

Review in Cost effectiveness and resource allocation : C/E, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Budget impact analysis of breast cancer medications: a systematic review.Journal of pharmaceutical policy and practice · 2022
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lu HanSchool of Health Management/Public Health, Harbin Medical University, Harbin, 150081, China.
Xin ZhangSchool of Health Management/Public Health, Harbin Medical University, Harbin, 150081, China.
Wen-Qi FuSchool of Health Management/Public Health, Harbin Medical University, Harbin, 150081, China.
Cheng-Yao SunSchool of Health Management/Public Health, Harbin Medical University, Harbin, 150081, China.
Xian-Ming ZhaoTumor Radiotherapy Center, Harbin the First Hospital, Harbin, 150010, China.
Liang-Ru ZhouSchool of Health Management/Public Health, Harbin Medical University, Harbin, 150081, China.
Guo-Xiang LiuSchool of Health Management/Public Health, Harbin Medical University, Harbin, 150081, China. lgx6301@163.com.

Funding

National Key research and development plan of China 2017YFC1308700National Key research and development plan of China 2017YFC1308705
6 · The paper itself

Abstract

backgroundBudget impact analyses (BIAs) are used for reimbursement decisions and drug access medical insurance, as a supplement to cost-effectiveness analyses (CEAs).

objectivesWe systematically reviewed BIAs for antitumor drugs of lung cancer to provide reference for high-value drug budget impact analyses and decision making.

methodsWe conducted a literature search on PubMed, EMbase, The Cochrane Library, China National Knowledge Infrastructure and Wanfang Data Knowledge Service Platform from 2010 to 2019. The methodological indicators and result information of the budget impact analyses were extracted and evaluated for quality.

resultsA total of 14 studies on the budget impact for antitumor drugs of lung cancer were included, and the overall quality was good. Half of studies were from developed countries. Nine of the studies were designed using the BIA cost calculation model, and two were simulated using the Markov model Monte Carlo model. From all studies, only 14.3% reported model validation. The budget impact results of the same drug in different countries were inconsistent.

conclusionsIncluded studies evaluating budget impact analyses for anti-tumor drugs of lung cancer showed variability in the methodological framework for BIAs. The budget impact analyses of high-value drugs need to be more stringent to ensure the accuracy of the parameters, and should provide reliable results based on real data to decision-making departments, which should carefully consider access to lung cancer drugs.

Indexed as

Antitumor drugsBudget impact analysesLung cancer

Identifiers

PMID33292288
PMCPMC7706257

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.