Evidence map›Paper›PMID 33292099›Full record

ArticleJournal of the Royal Society, Interface2020

Accumulation of dead cells from contact killing facilitates coexistence in bacterial biofilms.

Gabi Steinbach, Cristian Crisan, Siu Lung Ng, Brian K Hammer, Peter J Yunker

Abstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  14. Vertical growth dynamics of biofilms.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gabi SteinbachSchool of Physics, Georgia Institute of Technology, Atlanta, GA, USA.
Cristian CrisanCenter for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, GA, USA.
Siu Lung NgCenter for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, GA, USA.
Brian K HammerCenter for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, GA, USA.
Peter J YunkerSchool of Physics, Georgia Institute of Technology, Atlanta, GA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial communities are governed by a wide variety of social interactions, some of which are antagonistic with potential significance for bacterial warfare. Several antagonistic mechanisms, such as killing via the type VI secretion system (T6SS), require killer cells to directly contact target cells. The T6SS is hypothesized to be a highly potent weapon, capable of facilitating the invasion and defence of bacterial populations. However, we find that the efficacy of contact killing is severely limited by the material consequences of cell death. Through experiments with

Indexed as

Type VI Secretion SystemsVibrio choleraeBacterial ProteinsBiofilmsBacterial ProteinsType VI Secretion Systemsantagonismbacteriaemergence

Identifiers

PMID33292099
PMCPMC7811593

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.