Evidence map›Paper›PMID 33291949›Full record

ArticleBiological research for nursing2021

Engaging Adolescent and Young Adults in Microbiome Sample Self-Collection: Strategies for Success.

Chen X Chen, Janet S Carpenter, Tabitha Murphy, Patricia Brooks, J Dennis Fortenberry

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Biological research for nursing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. The Vaginal Microbiome and Reproductive Health in Adolescents and Adults.Journal of pediatric and adolescent gynecology · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chen X Chen15841Indiana University School of Nursing, Indianapolis, IN, USA.ORCID 0000-0002-6902-1227
Janet S Carpenter15841Indiana University School of Nursing, Indianapolis, IN, USA.
Tabitha Murphy15841Indiana University School of Nursing, Indianapolis, IN, USA.
Patricia BrooksDepartment of Pediatrics, 15841Indiana University School of Medicine, Indianapolis, IN, USA.
J Dennis FortenberryDepartment of Pediatrics, 15841Indiana University School of Medicine, Indianapolis, IN, USA.
Indiana University – Purdue University Indianapolis · USIndiana University School of Medicine

Funding

Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Translating Measures of Visual Experience to Children with Autism and Down SyndromeKL2TR002530 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI ROBB, SHERI L · 2018 to 2022
$4.8M
NCATS NIH HHS KL2 TR002530NCATS NIH HHS UL1 TR002529
6 · The paper itself

Abstract

Human microbiome research provides rich opportunities to elucidate factors influencing health, uncover novel biomarkers, and expand disease treatment options. A well-conducted microbiome study depends not only on a rigorous design but also on successfully engaging participants in collecting quality samples. In this paper, we aim to describe (1) strategies our team used to engage adolescents and young adults in vaginal and gut microbiome sample self-collection and (2) their effectiveness. In our prospective, longitudinal, feasibility study of 20 female adolescents and young adults, research participants self-collected vaginal and gut microbiome samples at home. Using a participatory and iterative process, we developed strategies to engage participants in sample self-collection, including (1) providing clear instructions to ensure comprehension and buy-in, (2) providing a user-friendly take-home package, (3) minimizing disgust/embarrassment associated with sample collection, and (4) follow-up communications to facilitate sample collections and return. With these strategies, we achieved 100% participant retention and 100% sample return rates. All samples (

Indexed as

Gastrointestinal MicrobiomeMicrobiotaAdolescentFemaleHumansProspective StudiesRNA, Ribosomal, 16SSpecimen HandlingYoung AdultRNA, Ribosomal, 16Sbiospecimen collectionbiospecimen self-collectiongut microbiomehuman microbiomelongitudinal studiesvaginal microbiome

Identifiers

PMID33291949
PMCPMC8755945
OpenAlexW3110792975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.