ArticleThe Journal of chemical physics2020
Combining the best of two worlds: Stimulated Raman excited fluorescence.
Article in The Journal of chemical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed.
- Far-field single-molecule vibrational spectroscopy and imaging.Chemical science · 2026Review
- Fluorescence-free single-molecule microscopy via electronic resonance stimulated Raman scattering.Nature communications · 2026Article
- Electrode- and Label-Free Assessment of Electrophysiological Firing Rates through Cytochrome C Monitoring via Raman Spectroscopy.ACS sensors · 2025Article
- Toward the Next Frontiers of Vibrational Bioimaging.Chemical & biomedical imaging · 2023Review
- Super-multiplexed vibrational probes: Being colorful makes a difference.Current opinion in chemical biology · 2022Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The pursuit of a hybrid spectroscopy that combines the superb sensitivity of fluorescence and the high chemical specificity of Raman scattering has lasted for 40 years, with multiple experimental and theoretical attempts in the literature. It was only recently that the stimulated Raman excited fluorescence (SREF) process was successfully observed in a broad range of fluorophores. SREF allows single-molecule vibrational spectroscopy and imaging in the optical far field without relying on plasmonic enhancement. In this perspective, we will first review the historical efforts that lead to the successful excitation and detection of SREF, followed by the underlying physical principles, then the remaining technical challenges will be discussed, and, at last, the future opportunities in this old but yet newly emerged spectroscopy are outlined.
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Registered trials
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