Evidence map›Paper›PMID 33291565›Full record

ArticleAntibiotics (Basel, Switzerland)2020

Impact and Sustainability of Antibiotic Stewardship in Pediatric Emergency Departments: Why Persistence Is the Key to Success.

Elisa Barbieri, Maia De Luca, Marta Minute, Carmen D'Amore, Marta Luisa Ciofi Degli Atti, Stefano Martelossi, Carlo Giaquinto, Liviana Da Dalt, Theoklis Zaoutis, Daniele Dona

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

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  14. Use of the Bacterial Lysate OM-85 in the Paediatric Population in Italy: A Retrospective Cohort Study.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Elisa BarbieriDivision of Pediatric Infectious Diseases, Department of Women's and Children's Health, University of Padova, 35131 Padova, Italy.ORCID 0000-0003-0850-8784
Maia De LucaUnit of Immune and Infectious Diseases, Academic Department of Pediatrics, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Marta MinutePediatric Unit, Ca' Foncello's Hospital, 31100 Treviso, Italy.
Carmen D'AmoreUnit of Clinical Epidemiology, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Marta Luisa Ciofi Degli AttiUnit of Clinical Epidemiology, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0001-6492-4497
Stefano MartelossiPediatric Unit, Ca' Foncello's Hospital, 31100 Treviso, Italy.
Carlo GiaquintoDivision of Pediatric Infectious Diseases, Department of Women's and Children's Health, University of Padova, 35131 Padova, Italy.
Liviana Da DaltPediatric Emergency Department, Department of Women's and Children's Health, University Hospital of Padua, 2-35128 Padova, Italy.
Theoklis ZaoutisDivision of Infectious Diseases and the Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Daniele DonaDivision of Pediatric Infectious Diseases, Department of Women's and Children's Health, University of Padova, 35131 Padova, Italy.
University of Padua · ITBambino Gesù Children's Hospital · ITCa' Foncello Hospital · ITChildren's Hospital of Philadelphia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic stewardship programs proved to be effective in improving prescribing appropriateness. This multicenter quasi-experimental study, aimed to assesses the stewardship impact on antibiotics prescribing in different semesters from 2014 to 2019 in three pediatric emergency departments (Center A, B, and C) in Italy. All consecutive patients diagnosed with acute otitis media or pharyngitis were evaluated for inclusion. Two different stewardship were adopted: for Center A and B, clinical pathways were implemented and disseminated, and yearly lectures were held, for Center C, only pathways were implemented. Broad-spectrum prescription rates decreased significantly by 80% for pharyngitis and 29.5 to 55.2% for otitis after the implementation. In Center C, rates gradually increased from the year after the implementation. Amoxicillin dosage adjusted to pharyngitis recommendations in Center C (53.7 vs. 51.6 mg/kg/die;

Indexed as

acute otitis mediaantibiotic stewardshipantibiotic usechildrenclinical pathwaysemergency departmentspharyngitisprescribing appropriateness

Identifiers

PMID33291565
PMCPMC7761799
OpenAlexW3108088739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.