Evidence map›Paper›PMID 33291543›Full record

ArticleBiology2020

The Effects of Pre-Storage Leukoreduction on the Conservation of Bovine Whole Blood in Plastic Bags.

Brena Peleja Vinholte, Rejane Dos Santos Sousa, Francisco Flávio Vieira Assis, Osvaldo Gato Nunes Neto, Juliana Machado Portela, Gilson Andrey Siqueira Pinto, Enrico Lippi Ortolani, Fernando José Benesi, Raimundo Alves Barrêto Júnior, Antonio Humberto Hamad Minervino

Open access · goldAbstract read
In one paragraph

Article in Biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Assessment of Donkey (Biology · 2021
    Article
  4. Cellular and Biochemical Effects of Combined X-Ray Radiation and Storage on Whole Blood.Dose-response : a publication of International Hormesis Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Brena Peleja VinholteLaboratory of Animal Health, LARSANA, Federal University of Western Pará, UFOPA, Rua Vera Paz, s/n Bairro Salé, Santarém 68040-255, PA, Brazil.
Rejane Dos Santos SousaDepartment of Clinical Science, College of Veterinary Medicine and Animal Science, University of Sao Paulo (FMVZ/USP, Av. Prof. Dr. Orlando Marques de Paiva, 87, Cidade Universitária, Butantã, São Paulo 05508-270, SP, Brazil.
Francisco Flávio Vieira AssisLaboratory of Animal Health, LARSANA, Federal University of Western Pará, UFOPA, Rua Vera Paz, s/n Bairro Salé, Santarém 68040-255, PA, Brazil.
Osvaldo Gato Nunes NetoLaboratory of Animal Health, LARSANA, Federal University of Western Pará, UFOPA, Rua Vera Paz, s/n Bairro Salé, Santarém 68040-255, PA, Brazil.
Juliana Machado PortelaLaboratory of Animal Health, LARSANA, Federal University of Western Pará, UFOPA, Rua Vera Paz, s/n Bairro Salé, Santarém 68040-255, PA, Brazil.
Gilson Andrey Siqueira PintoLaboratory of Animal Health, LARSANA, Federal University of Western Pará, UFOPA, Rua Vera Paz, s/n Bairro Salé, Santarém 68040-255, PA, Brazil.
Enrico Lippi OrtolaniDepartment of Clinical Science, College of Veterinary Medicine and Animal Science, University of Sao Paulo (FMVZ/USP, Av. Prof. Dr. Orlando Marques de Paiva, 87, Cidade Universitária, Butantã, São Paulo 05508-270, SP, Brazil.
Fernando José BenesiDepartment of Clinical Science, College of Veterinary Medicine and Animal Science, University of Sao Paulo (FMVZ/USP, Av. Prof. Dr. Orlando Marques de Paiva, 87, Cidade Universitária, Butantã, São Paulo 05508-270, SP, Brazil.
Raimundo Alves Barrêto JúniorDepartment of Animal Science, Federal Rural University of the Semiarid Region, UFERSA, Av. Francisco Mota, 572-Bairro Costa e Silva, Mossoró 59625-900, RN, Brazil.
Antonio Humberto Hamad MinervinoLaboratory of Animal Health, LARSANA, Federal University of Western Pará, UFOPA, Rua Vera Paz, s/n Bairro Salé, Santarém 68040-255, PA, Brazil.ORCID 0000-0002-6742-3652
Universidade Federal do Oeste do Pará · BRUniversidade de São Paulo · BRUniversidade Federal Rural do Semi-Árido · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leukoreduction (LR) is a technique that consists of reducing the number of leukocytes in whole blood or blood components that can contribute to decreasing storage lesions and the occurrence of post-transfusion complications. We propose that using a blood bag with pre-storage leukocyte filtration is sufficient for blood conservation under field conditions. Ten healthy Nelore cows were used. Whole blood was sampled from each animal and stored at 2 to 6 °C in CPD/SAG-M (citrate phosphate dextrose bag with a saline, adenine, glucose, mannitol satellite bag) triple bags (Control) and in CPD/SAG-M quadruple bags with a leukocyte filter (Filter). At baseline and after 7, 14, 21, 28, 35, and 42 days (D0, D7, D14, D21, D28, D35, and D42, respectively), complete hematological, blood gas, and biochemical evaluations were determined. The filtered bag removed 99.3% of white blood cells from cattle blood, and the entire filtration process was performed in the field. There was a reduction in the number of red blood cells (RBCs) in both groups from D14 onward, with a decrease of 19.7% and 17.1% at D42 for the Control and Filter bags, respectively. The hemoglobin (Hb) concentration had variation in both groups. Potassium, pO

Indexed as

blood storagecattletransfusion reactionswhite blood cells

Identifiers

PMID33291543
PMCPMC7761855
OpenAlexW3109008978

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.