Evidence map›Paper›PMID 33291403›Full record

ReviewCells2020

Propagation and Maintenance of Cancer Stem Cells: A Major Influence of the Long Non-Coding RNA

Clément Lecerf, Evodie Peperstraete, Xuefen Le Bourhis, Eric Adriaenssens

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Cells · 2026
    Review
  3. Review
  4. Research progress ofFrontiers in immunology · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Long non-coding RNAs: Key regulators of stemness in breast cancer.Frontiers in cell and developmental biology · 2025
    Review
  9. Review
  10. Review
  11. Review
  12. IncreasedInternational journal of molecular sciences · 2024
    Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Long noncoding RNA (lncRNA)Genes & diseases · 2023
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Clément LecerfUniv. Lille, CNRS, INSERM, CHU Lille, UMR 9020 - UMR 1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000 Lille, France.
Evodie PeperstraeteUniv. Lille, CNRS, INSERM, CHU Lille, UMR 9020 - UMR 1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000 Lille, France.
Xuefen Le BourhisUniv. Lille, CNRS, INSERM, CHU Lille, UMR 9020 - UMR 1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000 Lille, France.ORCID 0000-0001-6790-6358
Eric AdriaenssensUniv. Lille, CNRS, INSERM, CHU Lille, UMR 9020 - UMR 1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000 Lille, France.
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer stem cells (CSCs) represent a rare population of tumor cells that exhibit stem cell properties with the abilities of self-renewal and differentiation. These cells are now widely accepted to be responsible for tumor initiation, development, resistance to conventional therapies, and recurrence. Thus, a better understanding of the molecular mechanisms involved in the control of CSCs is essential to improve patient management in terms of diagnostics and therapies. CSCs are regulated by signals of the tumor microenvironment as well as intrinsic genetic and epigenetic modulators.

Indexed as

Gene Expression Regulation, NeoplasticAllelesAnimalsApoptosisCell ProliferationDrug Resistance, NeoplasmEpigenesis, GeneticHumansHypoxiaMiceNeoplasm MetastasisNeoplasm Recurrence, LocalNeoplasmsNeoplastic Stem CellsRNA, Long NoncodingSignal TransductionH19 long non-coding RNARNA, Long Noncodingcancer stem cellsexosomesH19lncRNAnon-coding RNAreprogramming factorstumorigenicity

Identifiers

PMID33291403
PMCPMC7762009
OpenAlexW3112957674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.