ArticleAntibiotics (Basel, Switzerland)2020
Do Prosthetic Joint Infections Worsen the Functional Ambulatory Outcome of Patients with Joint Replacements? A Retrospective Matched Cohort Study.
Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- A systematic review and meta-analysis comparing outcomes following total knee arthroplasty for rheumatoid arthritis versus for osteoarthritis.BMC musculoskeletal disorders · 2023Pooled it
- A Comparison of Health-Related Quality of Life in Patients with Periprosthetic Joint Infection, Patients with Fracture-Related Infections and the General Population-A Multicenter Analysis of 384 Patients from the Section "Musculoskeletal Infections" of the German Society for Orthopaedics and Traumatology.Journal of clinical medicine · 2025Article
- Mortality, patient-reported outcome measures, and the health economic burden of prosthetic joint infection.EFORT open reviews · 2023Review
- Repurposed Fenoprofen Targeting SaeR AttenuatesACS central science · 2023Article
- A desirability of outcome ranking (DOOR) for periprosthetic joint infection - a Delphi analysis.Journal of bone and joint infection · 2022Article
- [Prosthetic infections and the increasing importance of psychological comorbidities : An epidemiological analysis for Germany from 2009 through 2019].Der Orthopade · 2021Article
- Intra-Articular Injections Prior to Total Knee Arthroplasty Do Not Increase the Risk of Periprosthetic Joint Infection: A Prospective Cohort Study.Antibiotics (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo assess the effect on the functional ambulatory outcome of postoperative joint infection (PJI) cured at the first treatment attempt versus not developing PJI in patients with hip and knee prostheses.
methodsIn a single-hospital retrospectively matched cohort study, each patient with PJI between 2007 and 2016 was matched on age, sex, type of prosthesis and year of implantation with two other patients with uninfected arthroplasties. The definition of a PJI cure included infection eradication, no further surgical procedures, no PJI-related mortality and no suppressive antibiotics. Functional ambulatory status evaluated one year after the last surgery was classified into four simple categories: able to walk without assistance, able to walk with one crutch, able to walk with two crutches, and unable to walk. Patients with total hip arthroplasties (THA), total knee arthroplasties (TKA) and partial hip arthroplasty (PHA) were analysed separately.
resultsA total of 109 PJI patients (38 TKA, 41 THA, 30 PHA) and 218 non-PJI patients were included. In a model adjusted for clinically relevant variables, PJI was associated with a higher risk of needing an assistive device for ambulation (vs. walking without aid) among THA (adjusted odds ratio (OR) 3.10, 95% confidence interval (95% CI) 1.26-7.57;
conclusionsAmbulatory outcome in patients with hip and knee prostheses with postoperative PJI is worse than in patients who do not have PJI.
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