Evidence map›Paper›PMID 33291367›Full record

ArticleMolecules (Basel, Switzerland)2020

Effect of DODAB Nano-Sized Cationic Bilayer Fragments against

Thalita C S Ferreira, Ismael P Sauter, Lina Borda-Samper, Enyd Bentivoglio, Jarina P DaMata, Noemi N Taniwaki, Patrício R Orrego, Jorge E Araya, Nilton Lincopan, Mauro Cortez

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Supramolecular Nanostructures for Vaccines.Biomimetics (Basel, Switzerland) · 2021
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Thalita C S FerreiraDepartamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP 05508-000, Brazil.ORCID 0000-0001-8282-5708
Ismael P SauterDepartamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP 05508-000, Brazil.
Lina Borda-SamperDepartamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP 05508-000, Brazil.
Enyd BentivoglioDepartamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP 05508-000, Brazil.ORCID 0000-0002-8250-9788
Jarina P DaMataDepartamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP 05508-000, Brazil.ORCID 0000-0002-6117-7630
Noemi N TaniwakiInstituto Adolfo Lutz, São Paulo, SP 02146-000, Brazil.
Patrício R OrregoFacultad de Ciencias de la Salud, Departamento Biomédico, Universidad de Antofagasta, Antofagasta, CP 1270300, Chile.
Jorge E ArayaFacultad de Ciências de la Salud, Departamento de Tecnología Médica, Universidad de Antofagasta, Antofagasta, CP 1270300, Chile.
Nilton LincopanDepartamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP 05508-000, Brazil.ORCID 0000-0003-0161-5800
Mauro CortezDepartamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP 05508-000, Brazil.ORCID 0000-0001-6536-4647
Universidade de São Paulo · BRUniversidad de Antofagasta · CLInstituto Adolfo Lutz · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 312249/2017-9Conselho Nacional de Desenvolvimento Científico e Tecnológico 443816/2014-0Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Fundação de Amparo à Pesquisa do Estado de São Paulo 13/14087-0Fundação de Amparo à Pesquisa do Estado de São Paulo 13/15254-8Fundação de Amparo à Pesquisa do Estado de São Paulo 2012/24105-3Ministerio de Educación, Gobierno de Chile ANT1856Union Iberoamericana de Universidades (UIU-"Discovery of New Antiparasitic Agents", Proposal 1054, 1st and 2nd Research Collaboration Fund: 2017-2018 and 2019-2020 1054
6 · The paper itself

Abstract

The dioctadecyldimethylammonium bromide (DODAB) is a double-chained cationic lipid with potent bactericide and fungistatic activities; however, its toxicity on protozoan parasites is still unknown. Here, we show the antileishmanial activity of DODAB nano-sized cationic bilayer fragments on stationary-phase promastigotes and amastigotes of

Indexed as

AnimalsAntiprotozoal AgentsCationsLeishmania mexicanaLeishmaniasis, CutaneousLife Cycle StagesLipidsMacrophagesMiceMice, Inbred C57BLNanoparticlesQuaternary Ammonium CompoundsAntiprotozoal AgentsCationsdimethyldioctadecylammoniumLipidsQuaternary Ammonium Compoundsantileishmanial activitycationic bilayer fragmentsdioctadecyldimethylammonium bromide (DODAB)Leishmania amazonensis

Identifiers

PMID33291367
PMCPMC7730371
OpenAlexW3110128329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.