Evidence map›Paper›PMID 33291326›Full record

ArticleNanomaterials (Basel, Switzerland)2020

The Antifungal Mechanism of Amphotericin B Elucidated in Ergosterol and Cholesterol-Containing Membranes Using Neutron Reflectometry.

Robin Delhom, Andrew Nelson, Valerie Laux, Michael Haertlein, Wolfgang Knecht, Giovanna Fragneto, Hanna P Wacklin-Knecht

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Review
  3. Deciphering the multidrug resistance paradigm inAntimicrobial agents and chemotherapy · 2026
    Review
  4. Review
  5. Mono-Antibiotics (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Article
  8. Semisynthetic Amides of Amphotericin B and Nystatin AAntibiotics (Basel, Switzerland) · 2023
    Article
  9. Review
  10. Article
  11. Review
  12. Deletion of the Stress Response GeneJournal of fungi (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Robin DelhomInstitut Laue-Langevin, 71 Avenue des Martyrs, CS 20156, 38042 Grenoble CEDEX 9, France.ORCID 0000-0003-4609-6733
Andrew NelsonAustralian Centre for Neutron Scattering, Australian Nuclear Science and Technology Organization, Locked Bag 2001, Kirrawee DC, NSW 2232, Australia.ORCID 0000-0002-4548-3558
Valerie LauxInstitut Laue-Langevin, 71 Avenue des Martyrs, CS 20156, 38042 Grenoble CEDEX 9, France.
Michael HaertleinInstitut Laue-Langevin, 71 Avenue des Martyrs, CS 20156, 38042 Grenoble CEDEX 9, France.
Wolfgang KnechtDepartment of Biology, Lund University, Sölvegatan 35, 22362 Lund, Sweden.
Giovanna FragnetoInstitut Laue-Langevin, 71 Avenue des Martyrs, CS 20156, 38042 Grenoble CEDEX 9, France.ORCID 0000-0002-9896-3387
Hanna P Wacklin-KnechtEuropean Spallation Source ERIC, P.O. Box 176, 22100 Lund, Sweden.ORCID 0000-0002-5248-1147
Institut Laue-Langevin · FRLund University · SEAustralian Nuclear Science and Technology Organisation · AU

Funding

H2020 Research Infrastructures 654000Lunds Universitet Travel grantVetenskapsrådet 2016-01164
6 · The paper itself

Abstract

We have characterized and compared the structures of ergosterol- and cholesterol-containing 1-palmitoyl-2-oleoyl-

Indexed as

amphotericin Bcholesterolergosterollipid membranesneutron reflectionPOPC

Identifiers

PMID33291326
PMCPMC7762259
OpenAlexW3110730179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.