Evidence map›Paper›PMID 33291319›Full record

ArticleCancers2020

tRNA-Derived Fragments (tRFs) in Bladder Cancer: Increased 5'-tRF-LysCTT Results in Disease Early Progression and Patients' Poor Treatment Outcome.

Maria-Alexandra Papadimitriou, Margaritis Avgeris, Panagiotis Levis, Evangelia Ch Papasotiriou, Georgios Kotronopoulos, Konstantinos Stravodimos, Andreas Scorilas

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
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  6. The Roles of tRNA-Derived Fragments in Cancer: Updates and Perspectives.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. A novel tyrosine tRNA-derived fragment, tRFCellular & molecular biology letters · 2023
    Article
  14. Review
  15. Article
  16. tRNA-derived fragments (tRFs) in cancer.Journal of cell communication and signaling · 2023
    Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Maria-Alexandra PapadimitriouDepartment of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 157 01 Athens, Greece.
Margaritis AvgerisDepartment of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 157 01 Athens, Greece.ORCID 0000-0002-2135-9886
Panagiotis LevisFirst Department of Urology, "Laiko" General Hospital, School of Medicine, National and Kapodistrian University of Athens, 115 27 Athens, Greece.
Evangelia Ch PapasotiriouDepartment of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 157 01 Athens, Greece.
Georgios KotronopoulosFirst Department of Urology, "Laiko" General Hospital, School of Medicine, National and Kapodistrian University of Athens, 115 27 Athens, Greece.ORCID 0000-0002-8157-1029
Konstantinos StravodimosFirst Department of Urology, "Laiko" General Hospital, School of Medicine, National and Kapodistrian University of Athens, 115 27 Athens, Greece.
Andreas ScorilasDepartment of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 157 01 Athens, Greece.ORCID 0000-0003-2427-4949
National and Kapodistrian University of Athens · GR

Funding

This research has been co-financed by the European Regional Development Fund of the European Union and Greek national funds through the Operational Program Competitiveness, Entrepreneurship and Innovation, under the call RESEARCH - CREATE - INNOVATE (proj T2EDK-02196
6 · The paper itself

Abstract

The heterogeneity of bladder cancer (BlCa) prognosis and treatment outcome requires the elucidation of tumors' molecular background towards personalized patients' management. tRNA-derived fragments (tRFs), although originally considered as degradation debris, represent a novel class of powerful regulatory non-coding RNAs.

Indexed as

5′-tRFsbladder cancerbladder tumorsbladder urothelial carcinomancRNAsnon coding RNAstRNA-derived fragmentstRNA fragmentstRNA-Lys-CTTtRNALysCTT

Identifiers

PMID33291319
PMCPMC7762106
OpenAlexW3112230377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.