Evidence map›Paper›PMID 33291299›Full record

ArticleViruses2020

Multiple SARS-CoV-2 Introductions Shaped the Early Outbreak in Central Eastern Europe: Comparing Hungarian Data to a Worldwide Sequence Data-Matrix.

Gábor Kemenesi, Safia Zeghbib, Balázs A Somogyi, Gábor Endre Tóth, Krisztián Bányai, Norbert Solymosi, Peter M Szabo, István Szabó, Ádám Bálint, Péter Urbán and 12 more

Abstract readComparative Study
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Infection Prevention Performance among In-Flight Cabin Crew in South Korea.International journal of environmental research and public health · 2021
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Gábor KemenesiNational Laboratory of Virology, Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.ORCID 0000-0001-9775-3065
Safia ZeghbibNational Laboratory of Virology, Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.
Balázs A SomogyiNational Laboratory of Virology, Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.
Gábor Endre TóthNational Laboratory of Virology, Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.
Krisztián BányaiInstitute for Veterinary Medical Research, Centre for Agricultural Research, 1093 Budapest, Hungary.
Norbert SolymosiCentre for Bioinformatics, University of Veterinary Medicine Budapest, 1078 Budapest, Hungary.ORCID 0000-0003-1783-2041
Peter M SzaboTranslational Discovery, Stromal Biology, Bristol-Myers Squibb, Princeton, NJ 08648, USA.
István SzabóVeterinary Diagnostic Directorate, National Food Safety Office, 1143 Budapest, Hungary.ORCID 0000-0003-4786-8475
Ádám BálintVeterinary Diagnostic Directorate, National Food Safety Office, 1143 Budapest, Hungary.
Péter UrbánBioinformatics Research Group, Genomics and Bioinformatics Core Facility, Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.
Róbert HerczegBioinformatics Research Group, Genomics and Bioinformatics Core Facility, Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.
Attila GyeneseiBioinformatics Research Group, Genomics and Bioinformatics Core Facility, Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.
Ágnes NagyMedical Centre, Hungarian Defense Forces, 1114 Budapest, Hungary.
Csaba István PereszlényiMedical Centre, Hungarian Defense Forces, 1114 Budapest, Hungary.
Gergely Csaba BabinszkyMedical Centre, Hungarian Defense Forces, 1114 Budapest, Hungary.
Gábor DudásMedical Centre, Hungarian Defense Forces, 1114 Budapest, Hungary.
Gabriella TerhesInstitute of Clinical Microbiology, Faculty of Medicine, University of Szeged, 6720 Szeged, Hungary.ORCID 0000-0002-7301-9672
Viktor ZöldiIndependent Researcher, 1301 Vantaa, Finland.
Róbert LovasInstitute for Computer Science and Control (SZTAKI), Eötvös Loránd Research Network, 1111 Budapest, Hungary.
Szabolcs TenczerInstitute for Computer Science and Control (SZTAKI), Eötvös Loránd Research Network, 1111 Budapest, Hungary.ORCID 0000-0002-7646-1116
László KornyaCentral Hospital of Southern Pest-National Institute of Hematolgy and Infectious Diseases, 1476 Budapest, Hungary.
Ferenc JakabNational Laboratory of Virology, Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe Acute Respiratory Syndrome Coronavirus 2 is the third highly pathogenic human coronavirus in history. Since the emergence in Hubei province, China, during late 2019, the situation evolved to pandemic level. Following China, Europe was the second epicenter of the pandemic. To better comprehend the detailed founder mechanisms of the epidemic evolution in Central-Eastern Europe, particularly in Hungary, we determined the full-length SARS-CoV-2 genomes from 32 clinical samples collected from laboratory confirmed COVID-19 patients over the first month of disease in Hungary. We applied a haplotype network analysis on all available complete genomic sequences of SARS-CoV-2 from GISAID database as of 21 April 2020. We performed additional phylogenetic and phylogeographic analyses to achieve the recognition of multiple and parallel introductory events into our region. Here, we present a publicly available network imaging of the worldwide haplotype relations of SARS-CoV-2 sequences and conclude the founder mechanisms of the outbreak in Central-Eastern Europe.

Indexed as

Disease OutbreaksSequence Analysis, DNAChinaCOVID-19EuropeEurope, EasternGene Regulatory NetworksGenome, ViralHumansHungaryOropharynxRNA, ViralSARS-CoV-2RNA, Viralhuman coronavirusnetwork analysisoutbreakpandemicphylodynamicsSARS-CoV-2

Identifiers

PMID33291299
PMCPMC7762115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.