Evidence map›Paper›PMID 33291221›Full record

ArticleMolecules (Basel, Switzerland)2020

The Optimization of a Novel Hydrogel-Egg White-Alginate for 2.5D Tissue Engineering of Salivary Spheroid-Like Structure.

Yuli Zhang, Hieu M Pham, Jose G Munguia-Lopez, Joseph M Kinsella, Simon D Tran

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Carbon Dots Crosslinked Egg White Hydrogel for Tissue Engineering.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Hydrogels for Salivary Gland Tissue Engineering.Gels (Basel, Switzerland) · 2022
    Review
  15. Review
  16. Bioengineering in salivary gland regeneration.Journal of biomedical science · 2022
    Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yuli ZhangFaculty of Dentistry, McGill University, 3640 University Street, Montreal, QC H3A 0C7, Canada.
Hieu M PhamFaculty of Dentistry, McGill University, 3640 University Street, Montreal, QC H3A 0C7, Canada.
Jose G Munguia-LopezFaculty of Dentistry, McGill University, 3640 University Street, Montreal, QC H3A 0C7, Canada.ORCID 0000-0002-5173-6494
Joseph M KinsellaDepartment of Bioengineering, McGill University, 3480 University Street, Montreal, QC H3A 0E9, Canada.ORCID 0000-0002-3052-0782
Simon D TranFaculty of Dentistry, McGill University, 3640 University Street, Montreal, QC H3A 0C7, Canada.ORCID 0000-0001-5594-359X
McGill University · CA

Funding

Egg Farmers of Canada 252070Fonds de Recherche du Québec - Santé 281271Natural Sciences and Engineering Research Council of Canada 2017-05247
6 · The paper itself

Abstract

Hydrogels have been used for a variety of biomedical applications; in tissue engineering, they are commonly used as scaffolds to cultivate cells in a three-dimensional (3D) environment allowing the formation of organoids or cellular spheroids. Egg white-alginate (EWA) is a novel hydrogel which combines the advantages of both egg white and alginate; the egg white material provides extracellular matrix (ECM)-like proteins that can mimic the ECM microenvironment, while alginate can be tuned mechanically through its ionic crosslinking property to modify the scaffold's porosity, strength, and stiffness. In this study, a frozen calcium chloride (CaCl

Indexed as

Tissue EngineeringAlginatesCell ProliferationCells, CulturedCell SurvivalEgg WhiteHumansHydrogelsSalivary GlandsSpheroids, CellularTissue ScaffoldsAlginatesHydrogelsalginateegg whitehydrogelsalivary glandtissue engineering

Identifiers

PMID33291221
PMCPMC7730374
OpenAlexW3112386615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.