ReviewMicroorganisms2020
Untapped Potentials of Endophytic Fungi: A Review of Novel Bioactive Compounds with Biological Applications.
Review in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
77 citing papers in PubMed.
- Indole-3-Acetic Acid Biosynthesis by Endophytic Fungi and Its Association with Plant-Fungus Interactions.Journal of fungi (Basel, Switzerland) · 2026Review
- Extract of endophytic fungus Cepalotheca foveolata (N11) inhibits lytic bacteriophage: a study on activity, cytotoxicity, and chemical profiling.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Low Nitrogen Concentration and Acidic pH Enhance the Antifungal Activity AgainstMicroorganisms · 2026Article
- Evaluation of physcion isolated from endophytic Aspergillus fumigatus ASH3 as an antiviral agent against coxsackievirus B4 and herpes simplex virus type 1: in silico-supported in vitro study.Folia microbiologica · 2026Article
- The endophyteFrontiers in microbiology · 2026Article
- Computational Evaluation of Fusarium nygamai Compounds as AcrD Efflux Pump Protein Inhibitors of Salmonella Typhimurium.Molecular biotechnology · 2025Article
- Revealing Diversity in NRPS Gene Clusters Across Six Pathogenic Colletotrichum Species.Current microbiology · 2025Article
- Fungus-derived opine enhances plant photosynthesis.Journal of advanced research · 2025Article
- New Cyclopeptide and γ‑Butyrolactone Derivatives from an Endophytic Strain of Cophinforma mamane.ACS omega · 2025Article
- Investigating the antimicrobial and anticancer potential of culturable fungal endophytes isolated from the stems of Kirkia acuminata Oliv.BMC microbiology · 2025Article
- Enzymatic Glycosylation ofBiomolecules · 2025Review
- Exploring the Antimicrobial, Antioxidant and Extracellular Enzymatic Activities of Culturable Endophytic Fungi Isolated from the Leaves ofMicroorganisms · 2025Article
- Endophytic Fungal Diversity and Its Interaction Mechanism with Medicinal Plants.Molecules (Basel, Switzerland) · 2025Review
- Endophytic fungi isolated from Vietnamese nut grass (Heliyon · 2025Article
- The legacy of endophytes for the formation of bioactive agents, pigments, biofertilizers, nanoparticles and bioremediation of environment.World journal of microbiology & biotechnology · 2025Review
- Antagonism ofFrontiers in microbiology · 2025Article
- Bioactive Compounds From Saudi Arabian Fungi: A Systematic Review of Anticancer Potential.Clinical pharmacology : advances and applications · 2025Review
- Article
- Determination of Biological Activity and Biochemical Content of Ethanol Extract from Fruiting Body ofJournal of fungi (Basel, Switzerland) · 2024Article
- Bioprospecting Endophytic Fungi of Forest Plants for Bioactive Metabolites with Antibacterial, Antifungal, and Antioxidant Potentials.Molecules (Basel, Switzerland) · 2024Article
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the last century, endophytic fungi have gained tremendous attention due to their ability to produce novel bioactive compounds exhibiting varied biological properties and are, therefore, utilized for medicinal, pharmaceutical, and agricultural applications. Endophytic fungi reside within the plant tissues without showing any disease symptoms, thus supporting the physiological and ecological attributes of the host plant. Ground breaking lead compounds, such as paclitaxel and penicillin, produced by endophytic fungi have paved the way for exploring novel bioactive compounds for commercial usage. Despite this, limited research has been conducted in this valuable and unique niche area. These bioactive compounds belong to various structural groups, including alkaloids, peptides, steroids, terpenoids, phenols, quinones, phenols, and flavonoids. The current review focuses on the significance of endophytic fungi in producing novel bioactive compounds possessing a variety of biological properties that include antibacterial, antiviral, antifungal, antiprotozoal, antiparasitic, antioxidant, immunosuppressant, and anticancer functions. Taking into consideration the portal of this publication, special emphasis is placed on the antimicrobial and antiviral activities of metabolites produced by endophytes against human pathogens. It also highlights the importance of utilization of these compounds as potential treatment agents for serious life-threatening infectious diseases. This is supported by the fact that several findings have indicated that these bioactive compounds may significantly contribute towards the fight against resistant human and plant pathogens, thus motivating the need enhance the search for new, more efficacious and cost-effective antimicrobial drugs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.