Evidence map›Paper›PMID 33291057›Full record

ArticleAddictive behaviors2021

Evaluating a school-based science program that teaches the physiological effects of nicotine.

Judy L Cameron, Karlie Brasch, Damara Strong, Barbara Paul, Erin Cavanaugh, Shreya Thakur, Mia N Watson, Tyra Jennings, Sunil U Nayak, Scott M Rawls

Open access · greenAbstract read
In one paragraph

Article in Addictive behaviors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Judy L CameronDepartments of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, United States; The Pitt Science Outreach Program of the Clinical Translational Science Institute, University of Pittsburgh, Pittsburgh, PA 15213, United States. Electronic address: scott.rawls@temple.edu.
Karlie BraschThe College of General Studies, University of Pittsburgh, Pittsburgh, PA 15213, United States.
Damara StrongThe Pitt Science Outreach Program of the Clinical Translational Science Institute, University of Pittsburgh, Pittsburgh, PA 15213, United States.
Barbara PaulThe Pitt Science Outreach Program of the Clinical Translational Science Institute, University of Pittsburgh, Pittsburgh, PA 15213, United States.
Erin CavanaughChemical & Petroleum Engineering, University of Pittsburgh, Pittsburgh, PA 15213, United States.
Shreya ThakurDepartments of Biology, University of Pittsburgh, Pittsburgh, PA 15213, United States.
Mia N WatsonCenter for Substance Abuse Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, United States.
Tyra JenningsCenter for Substance Abuse Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, United States.
Sunil U NayakCenter for Substance Abuse Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, United States.
Scott M RawlsDepartment of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, United States; Center for Substance Abuse Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, United States.
University of Pittsburgh · USTemple University · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
Pilot Projects Core (PPC)P30DA013429 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI Munir Gunes Kutlu · 2000 to 2026
$34.6M
Planarians and the pharmacology of addiction: an in vivo model for K-12 educationR25DA033270 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI RAWLS, SCOTT M. · 2014 to 2017
$1.0M
NCATS NIH HHS UL1 TR001857NIDA NIH HHS P30 DA013429NIDA NIH HHS R25 DA033270
6 · The paper itself

Abstract

School-based drug prevention programs represent a widely endorsed public health goal, with an important aspect of knowledge-based curricula being education about the physiological effects of drugs. Nicotine is one of the world's most addictive substances and in this program we have used nicotine-induced mammalian-like behaviors in flatworms called planarians to successfully teach students (4th-12th grade; n = 1,616 students) about the physiological and addictive effects of nicotine. An initial study tested the change in knowledge about addictive substances in 6th-12th grade students after they completed a lab examining the effects of two concentrations of nicotine on the number of stereotypies (C-shaped spasms) planarians demonstrate in a 5-minute period of time. Lab discussion focused on developing and testing hypotheses, measurement reliability, and mechanisms of nicotine action. Surveys given pre- and post-lab experience showed that 6th grade students have significantly lower knowledge about nicotine than 7th-12th grade students (6th grade: 40.65 ± 0.78% correct, 7th-12th grade: 59.29 ± 1.71%, p < 0.001) pre-lab, but that students in all grades showed a significant increase in knowledge post-lab (p < 0.001). In 6th grade the lab was effective in improving knowledge about nicotine in urban, suburban and rural schools, p < 0.001, with students in suburban schools showing significantly greater knowledge both pre-test (urban: 37.62 ± 1.45%; suburban: 48.78 ± 1.62%; rural: 37.33 ± 0.99%; p < 0.001) and post-test (urban:60.60 ± 1.85%; suburban: 67.54 ± 1.82%; urban: 61.66 ± 1.18%; p < 0.001). A second study, modifying the lab so that the time spent observing the planarians is reduced to a 1-minute period, showed that students in both 4th and 5th grades had a significant increase in knowledge about the physiological and addictive effects of nicotine post-lab (p < 0.001).

Indexed as

NicotineSchoolsAnimalsHealth Knowledge, Attitudes, PracticeHumansReproducibility of ResultsRural PopulationStudentsNicotineAddictionBehaviorDrug preventionEducationNicotinePlanarians

Identifiers

PMID33291057
PMCPMC7785664
OpenAlexW3107285659

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.