ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2021
Functional magnetic resonance brain imaging of imagined walking to study locomotor function after stroke.
Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Role of Contralesional Corticoreticulospinal Tract Compensation in Walking Function After Stroke.Brain and behavior · 2026Trial
- Evaluating the Neural Underpinnings of Motivation for Walking Exercise.Physical therapy · 2024Trial
- Post-task resting-state fMRI of walking-related neural activity in patients with stroke: immediate and delayed brain network dynamics.Annals of medicine · 2026Article
- Mobile human brain imaging using functional ultrasound.Science advances · 2025Article
- Neural responses to social touch with different emotional valences: an fNIRS study.Social cognitive and affective neuroscience · 2025Article
- Motivation-related influences on fNIRS signals during walking exercise: a permutation entropy approach.Experimental brain research · 2023Article
- Neuropsychological Activations and Networks While Performing Visual and Kinesthetic Motor Imagery.Brain sciences · 2023Article
- Article
- A large, curated, open-source stroke neuroimaging dataset to improve lesion segmentation algorithms.Scientific data · 2022Article
- LASSO Homotopy-Based Sparse Representation Classification for fNIRS-BCI.Sensors (Basel, Switzerland) · 2022Article
- Mapping the human corticoreticular pathway with multimodal delineation of the gigantocellular reticular nucleus and high-resolution diffusion tractography.Journal of the neurological sciences · 2022Article
- Preliminary Outcomes of Combined Treadmill and Overground High-Intensity Interval Training in Ambulatory Chronic Stroke.Frontiers in neurology · 2022Article
- Mapping the corticoreticular pathway from cortex-wide anterograde axonal tracing in the mouse.Journal of neuroscience research · 2021Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveImagined walking has yielded insights into normal locomotor control and could improve understanding of neurologic gait dysfunction. This study evaluated brain activation during imagined walking in chronic stroke.
methodsTen persons with stroke and 10 matched controls completed a walking test battery and a magnetic resonance imaging session including imagined walking and knee extension tasks. Brain activations were compared between tasks and groups. Associations between activations and composite gait score were also calculated, while controlling for lesion load.
resultsStroke and worse gait score were each associated with lesser overall brain activation during knee extension but greater overall activation during imagined walking. During imagined walking, the stroke group significantly activated the primary motor cortex lower limb region and cerebellar locomotor region. Better walking function was associated with less activation of these regions and greater activation of medial superior frontal gyrus area 9.
conclusionsCompared with knee extension, imagined walking was less sensitive to stroke-related deficits in brain activation but better at revealing compensatory changes, some of which could be maladaptive. SIGNIFICANCE: The identified associations for imagined walking suggest potential neural mechanisms of locomotor adaptation after stroke, which could be useful for future intervention development and prognostication.
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