Evidence map›Paper›PMID 33290770›Full record

ReviewJournal of molecular and cellular cardiology2021

Mitochondrial Ca

Brian O'Rourke, Deepthi Ashok, Ting Liu

Open access · greenAbstract readReview
In one paragraph

Review in Journal of molecular and cellular cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Mechano-energetic uncoupling in heart failure.Nature reviews. Cardiology · 2025
    Review
  8. Article
  9. Review
  10. Metabolic Reprogramming in Heart Failure: From Energy Starvation to Therapeutic Targets.Current treatment options in cardiovascular medicine · 2025
    Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Mitochondrial CaJACC. Basic to translational science · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Brian O'RourkeThe Johns Hopkins University, Division of Cardiology, Department of Medicine, Baltimore, MD 21205, USA. Electronic address: bor@jhmi.edu.
Deepthi AshokThe Johns Hopkins University, Division of Cardiology, Department of Medicine, Baltimore, MD 21205, USA.
Ting LiuThe Johns Hopkins University, Division of Cardiology, Department of Medicine, Baltimore, MD 21205, USA.
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

Targeting Metabo-Redox Network Vulnerability in Heart Failure and Sudden DeathR01HL134821 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI FOSTER, D BRIAN, O'ROURKE, BRIAN · 2018 to 2021
$2.1M
Molecular Determinants of Mitochondrial Instability and ArrhythmiasR01HL137259 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI AKAR, FADI GABRIEL, O'ROURKE, BRIAN · 2017 to 2020
$2.0M
NHLBI NIH HHS R01 HL134821NHLBI NIH HHS R01 HL137259
6 · The paper itself

Abstract

Ca

Indexed as

AnimalsCalciumHeart FailureHumansIon TransportMitochondria, HeartOxidation-ReductionReactive Oxygen SpeciesCalciumReactive Oxygen SpeciesAnimal modelHeart failureMCUNCLXROSSudden cardiac death

Identifiers

PMID33290770
PMCPMC7880905
OpenAlexW3113366436

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.