Evidence map›Paper›PMID 33290723›Full record

ArticleDevelopmental cell2021

Messenger RNA 5' NAD

Xiang Yu, Matthew R Willmann, Lee E Vandivier, Sophie Trefely, Marianne C Kramer, Jeffrey Shapiro, Rong Guo, Eric Lyons, Nathaniel W Snyder, Brian D Gregory

Abstract read
In one paragraph

Article in Developmental cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. Arabidopsis DXO1- and RNMT1-Mediated mPlant, cell & environment · 2026
    Article
  2. Article
  3. RNA regulation in plants.Science China. Life sciences · 2026
    Review
  4. CDS-localized mNature plants · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Epigenetics in the modern era of crop improvements.Science China. Life sciences · 2025
    Review
  15. RNA mNature plants · 2025
    Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiang YuDepartment of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Matthew R WillmannSchool of Integrative Plant Science, Cornell University, Ithaca, NY 14853, USA.
Lee E VandivierDepartment of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Cell and Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Sophie TrefelyDepartment of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Center for Metabolic Disease Research, Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Marianne C KramerDepartment of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Cell and Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Jeffrey ShapiroDepartment of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Rong GuoDepartment of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Eric LyonsSchool of Plant Sciences, University of Arizona, Tucson, AZ 85721, USA; CyVerse, University of Arizona, Tucson, AZ 85721, USA.
Nathaniel W SnyderCenter for Metabolic Disease Research, Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Brian D GregoryDepartment of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Cell and Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: bdgregor@sas.upenn.edu.

Funding

Quantification of compartmentalized metabolism in eukaryotic systemsR01GM132261 · NIGMS · TEMPLE UNIV OF THE COMMONWEALTH · PI SNYDER, NATHANIEL W. · 2019 to 2023
$1.8M
NIGMS NIH HHS R01 GM132261
6 · The paper itself

Abstract

Although eukaryotic messenger RNAs (mRNAs) normally possess a 5' end N

Indexed as

Abscisic AcidArabidopsisArabidopsis ProteinsChloroplast ProteinsDNA-Binding ProteinsExoribonucleasesGene OntologyNADPlants, Genetically ModifiedRNA, MessengerRNA Processing, Post-TranscriptionalRNA, Small UntranslatedRNA StabilityTranscription FactorsTranscriptomeAbscisic AcidArabidopsis ProteinsAT4G17620 protein, ArabidopsisChloroplast ProteinsCONSTANS protein, ArabidopsisDNA-Binding ProteinsExoribonucleasesNADRNA, MessengerRNA, Small UntranslatedTranscription FactorsABAabscisic acidepitranscriptomeNAD cappingpost-transcriptional regulationRNA degradationRNA modificationRNA stability

Identifiers

PMID33290723
PMCPMC8934595

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.