ArticleAging2020
Cause of death among patients with colorectal cancer: a population-based study in the United States.
Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Cardiovascular mortality in people with cancer compared to the general population: A systematic review and meta-analysis.Cancer medicine · 2024Pooled it
- Mortality rate and predictors of colorectal cancer patients in Ethiopia: a systematic review and meta-analysis.BMC cancer · 2024Pooled it
- Cancer Patients Mortality From Other Causes: A European Population-Based Study.Cancer medicine · 2026Article
- Temporal trends in the cause of death of patients with colon and rectal cancer.Cancer causes & control : CCC · 2026Article
- The role of extracellular vesicles in the transport and regulation of novel inflammatory mediators in IBD and its associated CRC.Frontiers in cell and developmental biology · 2026Review
- Causes of death after surgery among cancer patients: a population-based cohort study.International journal of surgery (London, England) · 2026Article
- Suicide mortality and suicidal ideation among patients with colorectal cancer: a systematic review and meta-analysis.EClinicalMedicine · 2025Article
- The impact of cancer survivors' extra risk of noncancer mortality on net survival estimation.American journal of epidemiology · 2025Article
- Cancer history and mortality risk in acute myocardial infarction: Insights from the Japan AMI registry.International journal of cardiology. Heart & vasculature · 2025Article
- Spatial patterns of colorectal cancer survival rates in Malaysia, 2013-2018.Cancer causes & control : CCC · 2025Article
- Differential Colorectal Cancer Mortality Across Racial and Ethnic Groups: Impact of Socioeconomic Status, Clinicopathology, and Treatment-Related Factors.Cancer medicine · 2025Article
- Integrating next-generation sequencing and artificial intelligence for the identification and validation of pathogenic variants in colorectal cancer.Frontiers in oncology · 2025Article
- Development and validation of a risk predictive nomogram for colon cancer-specific mortality: a competing risk model based on the SEER database.Discover oncology · 2024Article
- Nomogram predicting the cardiovascular disease mortality for older patients with colorectal cancer: A real-world population-based study.World journal of cardiology · 2024Article
- Safety and feasibility of chemotherapy followed by liver transplantation for patients with definitely unresectable colorectal liver metastases: insights from the TransMet randomised clinical trial.EClinicalMedicine · 2024Article
- The multifaceted role of extracellular vesicles (EVs) in colorectal cancer: metastasis, immune suppression, therapy resistance, and autophagy crosstalk.Journal of translational medicine · 2024Review
- Ultra-processed food consumption and mortality among patients with stages I-III colorectal cancer: a prospective cohort study.EClinicalMedicine · 2024Article
- Age-related Disparities in Pan-Cancer Mortality and Causes of Death: Analysis of Surveillance, Epidemiology, and End Results (SEER) Data.Journal of Cancer · 2024Article
- Non cancer causes of death after gallbladder cancer diagnosis: a population-based analysis.Scientific reports · 2023Article
- Twenty-year experience in liver surgery in metastatic colorectal patients: a case series study in Ukraine.Annals of medicine and surgery (2012) · 2023Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
CRC (Colorectal cancer) is one of the most common causes of death worldwide and in the US (United States). In this study, we aim to perform a population-based analysis on the cause of death among patients with CRC in the US. A total of 834,510 CRC patients diagnosed between 1975 and 2016 in the US were selected from the SEER (Surveillance, Epidemiology, and End Results) program. Causes of death among CRC patients were characterized and SMRs (standardized mortality ratios) of death from non-cancer causes were calculated. Among all CRC patients included in this study, a total of 531,507 deaths were recorded, of which 51.3% were due to CRC, 10.3% were due to other cancers, and 38.4% were due to non-cancer causes. Recently, there has been a relative decrease in index-cancer deaths and an increase in non-cancer causes among CRC patients. The mortality risk from non-cancer rises with accumulating age and longer follow-up time. Cardiovascular diseases are the most prevalent non-cancer causes, accounting for 20.3% of all deaths among CRC patients. Compared with the general population, the mortality rate of non-cancer deaths among CRC patients is doubled (SMR, 2.02; 95% confidence interval, 2.01-2.03).
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