Evidence map›Paper›PMID 33289360›Full record

ArticleKorean journal of radiology2021

Radiomics of Non-Contrast-Enhanced T1 Mapping: Diagnostic and Predictive Performance for Myocardial Injury in Acute ST-Segment-Elevation Myocardial Infarction.

Quanmei Ma, Yue Ma, Tongtong Yu, Zhaoqing Sun, Yang Hou

Registry-linked trialAbstract read
In one paragraph

Article in Korean journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04682756 (A Multicenter Study on Early Diagnosis of NSTE-ACS Patients Based on Machine Learning Model), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04682756 unknown statusnot on this map

A Multicenter Study on Early Diagnosis of NSTE-ACS Patients Based on Machine Learning Model

Typeobservational_patient_registrySponsorFirst Affiliated Hospital of Xinjiang Medical UniversityRan2020 to 2022Enrolled2,500ConditionsNSTEMI - Non-ST Segment Elevation MI, Unstable AnginaArmsThe model of machine learning
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Development and evaluation of a radiomics model of restingAnnals of translational medicine · 2022
    Article
  14. Article
  15. Review
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  18. Magnetic Resonance Texture Analysis in Myocardial Infarction.Frontiers in cardiovascular medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Quanmei MaDepartment of Radiology, Shengjing Hospital of China Medical University, Shenyang, China.ORCID 0000-0002-5660-8264
Yue MaDepartment of Radiology, Shengjing Hospital of China Medical University, Shenyang, China.ORCID 0000-0002-4117-0319
Tongtong YuDepartment of Cardiology, Shengjing Hospital of China Medical University, Shenyang, China.ORCID 0000-0001-7525-6164
Zhaoqing SunDepartment of Cardiology, Shengjing Hospital of China Medical University, Shenyang, China.ORCID 0000-0002-1608-7396
Yang HouDepartment of Radiology, Shengjing Hospital of China Medical University, Shenyang, China. houyang1973@163.com.ORCID 0000-0002-9184-5441

Funding

CMUShengjing Hospital 501100015226
6 · The paper itself

Abstract

objectiveTo evaluate the feasibility of texture analysis on non-contrast-enhanced T1 maps of cardiac magnetic resonance (CMR) imaging for the diagnosis of myocardial injury in acute myocardial infarction (MI). MATERIALS AND

methodsThis study included 68 patients (57 males and 11 females; mean age, 55.7 ± 10.5 years) with acute ST-segment-elevation MI who had undergone 3T CMR after a percutaneous coronary intervention. Forty patients of them also underwent a 6-month follow-up CMR. The CMR protocol included T2-weighted imaging, T1 mapping, rest first-pass perfusion, and late gadolinium enhancement. Radiomics features were extracted from the T1 maps using open-source software. Radiomics signatures were constructed with the selected strongest features to evaluate the myocardial injury severity and predict the recovery of left ventricular (LV) longitudinal systolic myocardial contractility.

resultsA total of 1088 segments of the acute CMR images were analyzed; 103 (9.5%) segments showed microvascular obstruction (MVO), and 557 (51.2%) segments showed MI. A total of 640 segments were included in the 6-month follow-up analysis, of which 160 (25.0%) segments showed favorable recovery of LV longitudinal systolic myocardial contractility. Combined radiomics signature and T1 values resulted in a higher diagnostic performance for MVO compared to T1 values alone (area under the curve [AUC] in the training set; 0.88, 0.72,

conclusionThe combination of radiomics of non-contrast-enhanced T1 mapping and T1 values could provide higher diagnostic accuracy for MVO. Radiomics also provides incremental value in the prediction of LV longitudinal systolic myocardial contractility at six months.

Indexed as

Acute DiseaseAdultAgedArea Under CurveContrast MediaCoronary VesselsFemaleHumansImage Processing, Computer-AssistedMachine LearningMagnetic Resonance Imaging, CineMaleMiddle AgedPredictive Value of TestsRetrospective StudiesROC CurveContrast MediaMachine learningMagnetic resonance imagingMyocardial infarctionMyocardial reperfusion injury

Identifiers

PMID33289360
PMCPMC8005349

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.