ArticleKorean journal of radiology2021
Early-Phase SPECT/CT for Diagnosing Osteomyelitis: A Retrospective Pilot Study.
Article in Korean journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Bloodpool SPECT/CT offers enhanced sensitivity for the diagnosis of frozen shoulder.Annals of nuclear medicine · 2026Article
- Liposomal multimodal theranostics for bone disorders: from rational responsive delivery and biomimetic strategies to clinical translation.Journal of nanobiotechnology · 2026Review
- Study of the extent of surgical osteotomy in Cierny-Mader stages III and IV chronic osteomyelitis.BMC musculoskeletal disorders · 2025Article
- The differential diagnostic potential of SPECT/CT to detect osteomyelitis in foot or ankle: a systematic review.EFORT open reviews · 2025Article
- SPECT/CT and triple-phase bone scan: A valuable diagnostic approach for identifying indications for secondary patellar resurfacing in patients with unexplained anterior knee pain post-TKA.Arthroplasty (London, England) · 2025Article
- Case Report: Osteomyelitis in a giant panda (Frontiers in veterinary science · 2025Article
- Comparison of diagnostic efficacy betweenFrontiers in endocrinology · 2024Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this pilot study was to investigate the potential of early-phase single-photon emission computed tomography (SPECT)/computed tomography (CT) using technetium-99m methyl diphosphonate ( MATERIALS AND
methodsTwenty-one patients with suspected OM were enrolled retrospectively. Three-phase bone scan (TPBS), early-phase SPECT/CT (immediately after blood pool planar imaging), and delayed-phase SPECT/CT (immediately after delayed planar imaging) were performed. The final diagnoses were established through surgery or clinical follow-up for over 6 months. We compared three diagnostic criteria based on (I) TPBS alone, (II) combined TPBS and delayed-phase SPECT/CT, and (III) early-phase SPECT/CT alone.
resultsOM was diagnosed in 11 of 21 patients (nine surgically and two clinically). Of the 11 OM patients, criterion-I, criterion-II, and criterion-III were positive in six, seven, and 10 patients, respectively. Of the 10 non-OM patients, criterion-I, criterion-II, and criterion-III were negative in five, five, and seven patients, respectively. The sensitivity/specificity/accuracy of criterion-I, criterion-II, and criterion-III for diagnosing OM were 54.5%/50.0%/55.0%, 63.6%/50.0%/57.1%, and 90.9%/70.0%/87.5%, respectively.
conclusionThis pilot study demonstrated the potential of using the early-phase SPECT/CT to diagnose OM. Based on the results, prospective studies with a larger sample size should be conducted to confirm the efficacy of early-phase SPECT/CT.
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