Evidence map›Paper›PMID 33289290›Full record

ReviewCytometry. Part A : the journal of the International Society for Analytical Cytology2021

Biosafety during a pandemic: shared resource laboratories rise to the challenge.

Avrill M Aspland, Iyadh Douagi, Andrew Filby, Evan R Jellison, Lola Martinez, Diana Shinko, Adrian L Smith, Vera A Tang, Sherry Thornton

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Assessment of Biocontainment Efficacy and Flow Cytometric Impact of a Novel Platform in High Containment Laboratories.Applied biosafety : journal of the American Biological Safety Association · 2025
    Article
  3. Establishing a biosafety plan for a flow cytometry shared resource laboratory.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2022
    Article
  4. Risk awareness during operation of analytical flow cytometers and implications throughout the COVID-19 pandemic.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2021
    Article
  5. Biosafety during a pandemic: shared resource laboratories rise to the challenge.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Avrill M AsplandSydney Cytometry Core Research Facility, Centenary Institute, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0001-7406-0645
Iyadh DouagiFlow Cytometry Section, Research Technologies Branch, NIAID, NIH, Bethesda, Maryland, USA.ORCID 0000-0002-3221-8667
Andrew FilbyInnovation, Methodology and Application Research Theme, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0001-9078-4360
Evan R JellisonDepartment of Immunology, UCONN School of Medicine, Farmington, Connecticut, USA.
Lola MartinezBiotechnology Programme, Flow Cytometry Core Unit, Spanish National Cancer Research Center (CNIO), Madrid, Spain.
Diana ShinkoSydney Cytometry Core Research Facility, Centenary Institute, The University of Sydney, Sydney, New South Wales, Australia.
Adrian L SmithSydney Cytometry Core Research Facility, Centenary Institute, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0002-0505-0344
Vera A TangFaculty of Medicine, Department of Biochemistry, Microbiology, and Immunology, Flow Cytometry and Virometry Core Facility, University of Ottawa, Ottawa, Ontario, Canada.
Sherry ThorntonDivision of Rheumatology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.

Funding

Infectious Diseases Research Technologies Core - BethesdaZICAI001051 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI CHERRY, JAMES · 2009 to 2025
$226.1M
COVID-19 Instrumentation in the RTBZICAI001313 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI CHERRY, JAMES · 2020 to 2023
$2.6M
National Institute of Allergy and Infectious Diseases
6 · The paper itself

Abstract

Biosafety has always been an important aspect of daily work in any research institution, particularly for cytometry Shared Resources Laboratories (SRLs). SRLs are common-use spaces that facilitate the sharing of knowledge, expertise, and ideas. This sharing inescapably involves contact and interaction of all those within this working environment on a daily basis. The current pandemic caused by SARS-CoV-2 has prompted the re-evaluation of many policies governing the operations of SRLs. Here we identify and review the unique challenges SRLs face in maintaining biosafety standards, highlighting the potential risks associated with not only cytometry instrumentation and samples, but also the people working with them. We propose possible solutions to safety issues raised by the COVID-19 pandemic and provide tools for facilities to adapt to evolving guidelines and future challenges.

Indexed as

Containment of BiohazardsCOVID-19Flow CytometryHumansLaboratoriesRisk Assessmentbiosafety guidelinesCOVID-19cytometryemerging diseaseepidemicflow cytometrypandemicSARS-CoV-2shared resource laboratory (SRL)

Identifiers

PMID33289290
PMCPMC7753791

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.