ArticleScientific reports2020
Post-operative fracture risk assessment following tumor curettage in the distal femur: a hybrid in vitro and in silico biomechanical approach.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 10 citations in OpenAlex.
- The risk of pathological fractures after intralesional curettage in Atypical Cartilaginous Tumours: A retrospective cohort study.Journal of bone oncology · 2025Article
- Postoperative Fracture Risk in Giant Cell Tumor: A Case Report and Review of Literature.Cureus · 2023Article
- Risk factors of fracture following curettage for bone giant cell tumors of the extremities.BMC musculoskeletal disorders · 2022Article
- Can Patient-specific Finite Element Models Enter Clinical Practice as a Decision Support System?The archives of bone and joint surgery · 2021Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The distal femur is the predominant site for benign bone tumours and a common site for fracture following tumour removal or cementation. However, the lack of conclusive assessment criterion for post-operative fracture risk and appropriate devices for cement augmentation are serious concerns. Hence, a validated biomechanical tool was developed to assess bone strength, depending on the size and location of artificially created tumorous defects in the distal femora. The mechanics of the bone-cement interface was investigated to determine the main causes of reconstruction failure. Based on quantitative-CT images, non-linear and heterogeneous finite element (FE) models of human cadaveric distal femora with simulated tumourous defects were created and validated using in vitro mechanical tests from 14 cadaveric samples. Statistical analyses demonstrated a strong linear relationship (R
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Registered trials
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