Evidence map›Paper›PMID 33288788›Full record

ArticleScientific reports2020

Higher HbA1c levels associate with lower hippocampal serotonin transporter availability in non-diabetic adults with obesity.

Rico Grundmann, Michael Rullmann, Julia Luthardt, Franziska Zientek, Georg-Alexander Becker, Marianne Patt, Mohammed K Hankir, Matthias Blüher, Osama Sabri, Swen Hesse

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Rico GrundmannDepartment of Nuclear Medicine, University of Leipzig, Liebigstraße 18, 04103, Leipzig, Germany.
Michael RullmannDepartment of Nuclear Medicine, University of Leipzig, Liebigstraße 18, 04103, Leipzig, Germany.
Julia LuthardtDepartment of Nuclear Medicine, University of Leipzig, Liebigstraße 18, 04103, Leipzig, Germany.
Franziska ZientekIntegrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany.
Georg-Alexander BeckerDepartment of Nuclear Medicine, University of Leipzig, Liebigstraße 18, 04103, Leipzig, Germany.
Marianne PattDepartment of Nuclear Medicine, University of Leipzig, Liebigstraße 18, 04103, Leipzig, Germany.
Mohammed K HankirDepartment of Experimental Surgery, University Hospital Wuerzburg, Wuerzburg, Germany.
Matthias BlüherGerman Research Foundation Collaborative Research Center in Obesity Mechanisms 1052, University of Leipzig, Leipzig, Germany.
Osama SabriDepartment of Nuclear Medicine, University of Leipzig, Liebigstraße 18, 04103, Leipzig, Germany.
Swen HesseDepartment of Nuclear Medicine, University of Leipzig, Liebigstraße 18, 04103, Leipzig, Germany. swen.hesse@medizin.uni-leipzig.de.
Leipzig University · DEIFB Adiposity Diseases · DESana Kliniken Leipziger Land · DEUniversitätsklinikum Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current study aimed to investigate whether the in vivo availability of central serotonin reuptake transporters (5-HTT) is associated with plasma levels of glycosylated hemoglobin (HbA1c) in non-diabetic humans with obesity. 5-HTT availability was measured by using positron emission tomography (PET) imaging with the 5-HTT selective radiotracer [

Indexed as

AdultBlood GlucoseFemaleGlycated HemoglobinHippocampusHumansMaleMiddle AgedObesityPositron-Emission TomographySerotonin Plasma Membrane Transport ProteinsYoung AdultBlood GlucoseGlycated HemoglobinSerotonin Plasma Membrane Transport ProteinsSLC6A4 protein, human

Identifiers

PMID33288788
PMCPMC7721891
OpenAlexW3113040326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.