Evidence map›Paper›PMID 33288781›Full record

ArticleScientific reports2020

Confidence in subjective pain is predicted by reaction time during decision making.

Troy C Dildine, Elizabeth A Necka, Lauren Y Atlas

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. [AI in rehabilitation-application of artificial mental models for personalized medicine].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025
    Review
  5. Human ventromedial prefrontal cortex lesions enhance the effect of expectations on pain perception.Cortex; a journal devoted to the study of the nervous system and behavior · 2023
    Article
  6. Article
  7. Confidence of probabilistic predictions modulates the cortical response to pain.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Troy C DildineNational Center for Complementary and Integrative Health, National Institutes of Health, 10 Center Drive, Bethesda, MD, 20892, USA.
Elizabeth A NeckaNational Center for Complementary and Integrative Health, National Institutes of Health, 10 Center Drive, Bethesda, MD, 20892, USA.
Lauren Y AtlasNational Center for Complementary and Integrative Health, National Institutes of Health, 10 Center Drive, Bethesda, MD, 20892, USA. lauren.atlas@nih.gov.

Funding

Neural and psychological mechanisms of pain perception ZIAAT000030 · NCCIH · NATIONAL CENTER FOR COMPLEMENTARY & INTEGRATIVE HEALTH · PI ATLAS, LAUREN · 2015 to 2025
$3.8M
Intramural NIH HHS ZIA AT000030NCCIH NIH HHS ZIA-AT000030
6 · The paper itself

Abstract

Self-report is the gold standard for measuring pain. However, decisions about pain can vary substantially within and between individuals. We measured whether self-reported pain is accompanied by metacognition and variations in confidence, similar to perceptual decision-making in other modalities. Eighty healthy volunteers underwent acute thermal pain and provided pain ratings followed by confidence judgments on continuous visual analogue scales. We investigated whether eye fixations and reaction time during pain rating might serve as implicit markers of confidence. Confidence varied across trials and increased confidence was associated with faster pain rating reaction times. The association between confidence and fixations varied across individuals as a function of the reliability of individuals' association between temperature and pain. Taken together, this work indicates that individuals can provide metacognitive judgments of pain and extends research on confidence in perceptual decision-making to pain.

Indexed as

AdultDecision MakingDelivery of Health CareFemaleHumansMaleMetacognitionPainReaction TimeTemperature

Identifiers

PMID33288781
PMCPMC7721875

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.