Evidence map›Paper›PMID 33288743›Full record

ArticleNature communications2020

Cytosolic sequestration of the vitamin D receptor as a therapeutic option for vitamin D-induced hypercalcemia.

Daniela Rovito, Anna Y Belorusova, Sandra Chalhoub, Anna-Isavella Rerra, Elvire Guiot, Arnaud Molin, Agnès Linglart, Natacha Rochel, Gilles Laverny, Daniel Metzger

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

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  15. Design, Synthesis, Evaluation and Structure of Allenic 1α,25-Dihydroxyvitamin DChemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Daniela RovitoInstitut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.ORCID 0000-0001-5390-5477
Anna Y BelorusovaMedicinal Chemistry, Respiratory, Inflammation and Autoimmunity, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.ORCID 0000-0002-5229-4536
Sandra ChalhoubInstitut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.
Anna-Isavella RerraInstitut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.
Elvire GuiotInstitut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.
Arnaud MolinUniversité de Normandie, UNICAEN, CHU de Caen Normandie, Service de Génétique, EA 7450 BIOTARGEN, Caen, France.
Agnès LinglartReference Center for Rare Diseases of Calcium and Phosphorus Metabolism (OSCAR), Paris, France.
Natacha RochelInstitut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.ORCID 0000-0002-3573-5889
Gilles LavernyInstitut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France. laverny@igbmc.fr.ORCID 0000-0002-2666-6877
Daniel MetzgerInstitut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France. metzger@igbmc.fr.ORCID 0000-0002-5555-046X
Centre National de la Recherche Scientifique · FRInserm · FRAstraZeneca (Sweden) · SECentre Hospitalier Universitaire de Caen Normandie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The bioactive vitamin D

Indexed as

AnimalsCalcitriolCalciumCell LineCell Line, TumorCytosolGene ExpressionHeLa CellsHumansHypercalcemiaMaleMice, Inbred C57BLMice, KnockoutNuclear ProteinsProtein BindingRatsCalcitriolCalciumNuclear ProteinsReceptors, CalcitriolRNA-Binding ProteinsVdr protein, mouseVitamin DZK 168281

Identifiers

PMID33288743
PMCPMC7721737
OpenAlexW3111533782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.