Evidence map›Paper›PMID 33288737›Full record

ArticleAging2020

Genetic alterations in gastric cancer patients according to sex.

Li-Wen Hsu, Kuo-Hung Huang, Ming-Huang Chen, Wen-Liang Fang, Yee Chao, Su-Shun Lo, Anna Fen-Yau Li, Chew-Wun Wu, Yi-Ming Shyr

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Li-Wen HsuDivision of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.
Kuo-Hung HuangDivision of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.
Ming-Huang ChenSchool of Medicine, National Yang-Ming University, Taipei, Taiwan.
Wen-Liang FangDivision of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.
Yee ChaoSchool of Medicine, National Yang-Ming University, Taipei, Taiwan.
Su-Shun LoSchool of Medicine, National Yang-Ming University, Taipei, Taiwan.
Anna Fen-Yau LiSchool of Medicine, National Yang-Ming University, Taipei, Taiwan.
Chew-Wun WuDivision of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.
Yi-Ming ShyrDivision of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.
National Yang Ming Chiao Tung University · TWNational Yang Ming Chiao Tung University · TWNational Yang Ming University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To date, few reports have investigated the genetic alterations and clinicopathological features in gastric cancer (GC) according to sex. In total, 2673 GC patients receiving curative surgery were enrolled. Among the 2673 GC patients, 1979 (74.0%) patients were male. After propensity-score matching, 846 patients were enrolled for the analysis, including 423 males and 423 females. There was no significant difference in the clinicopathological features between the sexes. Regarding the initial recurrence pattern, the males were more likely to develop tumor recurrence and liver metastasis than the females, especially in stage III GC. Regarding the molecular analysis, the males had higher

Indexed as

AdenocarcinomaAgedAge FactorsB7-H1 AntigenClass I Phosphatidylinositol 3-KinasesDisease-Free SurvivalDNA-Binding ProteinsFemaleGastrectomyHumansLiver NeoplasmsMaleMicrosatellite InstabilityMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingARID1A protein, humanB7-H1 AntigenBRAF protein, humanCD274 protein, humanClass I Phosphatidylinositol 3-KinasesDNA-Binding ProteinsPIK3CA protein, humanProto-Oncogene Proteins B-rafProto-Oncogene Proteins c-aktPTEN PhosphohydrolasePTEN protein, humanTP53 protein, humanTranscription FactorsTumor Suppressor Protein p53clinicopathological featuregastric cancergenetic alterationprognosissex

Identifiers

PMID33288737
PMCPMC7835020
OpenAlexW3107186172

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.