Evidence map›Paper›PMID 33288711›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Pharmacoproteomics pinpoints HSP70 interaction for correction of the most frequent Wilson disease-causing mutant of ATP7B.

Mafalda Concilli, Raffaella Petruzzelli, Silvia Parisi, Federico Catalano, Francesco Sirci, Francesco Napolitano, Mario Renda, Luis J V Galietta, Diego Di Bernardo, Roman S Polishchuk

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
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  7. Trauma-toxicology: concepts, causes, complications.Naunyn-Schmiedeberg's archives of pharmacology · 2024
    Review
  8. Article
  9. Article
  10. Domperidone InhibitsToxins · 2023
    Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Mafalda ConcilliTelethon Institute of Genetics and Medicine, Pozzuoli, Naples 80078, Italy.
Raffaella PetruzzelliTelethon Institute of Genetics and Medicine, Pozzuoli, Naples 80078, Italy.ORCID 0000-0003-2868-4486
Silvia ParisiDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples 80131, Italy.ORCID 0000-0002-1944-9110
Federico CatalanoTelethon Institute of Genetics and Medicine, Pozzuoli, Naples 80078, Italy.ORCID 0000-0002-2520-8524
Francesco SirciTelethon Institute of Genetics and Medicine, Pozzuoli, Naples 80078, Italy.ORCID 0000-0002-9957-0358
Francesco NapolitanoTelethon Institute of Genetics and Medicine, Pozzuoli, Naples 80078, Italy.
Mario RendaTelethon Institute of Genetics and Medicine, Pozzuoli, Naples 80078, Italy.
Luis J V GaliettaTelethon Institute of Genetics and Medicine, Pozzuoli, Naples 80078, Italy.ORCID 0000-0001-8686-3461
Diego Di BernardoTelethon Institute of Genetics and Medicine, Pozzuoli, Naples 80078, Italy.
Roman S PolishchukTelethon Institute of Genetics and Medicine, Pozzuoli, Naples 80078, Italy; polish@tigem.it.ORCID 0000-0002-7698-1955
Telethon Institute Of Genetics And Medicine · ITInstitute of Biosciences and Bioresources · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathogenic mutations in the copper transporter

Indexed as

BenzimidazolesCells, CulturedCopperCopper-Transporting ATPasesDomperidoneEndoplasmic ReticulumHepatocytesHepatolenticular DegenerationHep G2 CellsHSP70 Heat-Shock ProteinsHumansMutation, MissenseNipecotic AcidsProtein TransportProteomicsATP7B protein, humanBenzimidazolesCopperCopper-Transporting ATPasesDomperidoneHS-72 compoundHSP70 Heat-Shock ProteinsNipecotic AcidsATP7Bcopper metabolismmutant correctionprotein quality controlWilson disease

Identifiers

PMID33288711
PMCPMC7768786
OpenAlexW3112735762

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.