Evidence map›Paper›PMID 33288474›Full record

ArticleJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society2021

Sensitive structural and functional measurements and 1-year pulmonary outcomes in pediatric cystic fibrosis.

Matthew M Willmering, David J Roach, Elizabeth L Kramer, Laura L Walkup, Zackary I Cleveland, Jason C Woods

Open access · greenAbstract read
In one paragraph

Article in Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Bias field correction in hyperpolarizedMagnetic resonance in medicine · 2022
    Article
  6. Review
  7. A year in review: Real world evidence, functional monitoring and emerging therapeutics in 2021.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2022
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Matthew M WillmeringCenter for Pulmonary Imaging Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, United States; Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, United States.
David J RoachCenter for Pulmonary Imaging Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, United States; Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, United States.
Elizabeth L KramerDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, United States; Department of Pediatrics, University of Cincinnati Medical Center, Cincinnati, OH 45229, United States.
Laura L WalkupCenter for Pulmonary Imaging Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, United States; Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, United States; Department of Pediatrics, University of Cincinnati Medical Center, Cincinnati, OH 45229, United States; Department of Biomedical Engineering, University of Cincinnati, Cincinnati, OH 45229, United States.
Zackary I ClevelandCenter for Pulmonary Imaging Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, United States; Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, United States; Department of Pediatrics, University of Cincinnati Medical Center, Cincinnati, OH 45229, United States; Department of Biomedical Engineering, University of Cincinnati, Cincinnati, OH 45229, United States.
Jason C WoodsCenter for Pulmonary Imaging Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, United States; Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, United States; Department of Pediatrics, University of Cincinnati Medical Center, Cincinnati, OH 45229, United States; Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, United States; Department of Physics, University of Cincinnati, Cincinnati, OH 45229, United States. Electronic address: Jason.Woods@cchmc.org.
Cincinnati Children's Hospital Medical Center · US

Funding

UTE MRI to monitor CF lung disease and response to CFTR modulation in young childrenR01HL131012 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI Raouf S. Amin, JASON C WOODS · 2016 to 2026
$6.8M
Pulmonary Development and Disease Pathogenesis Training ProgramT32HL007752 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI Francis Xavier McCormack, Anne-Karina Theresia Perl · 1994 to 2026
$6.3M
Validating Quantitative Magnetic Resonance Imaging Biomarkers of Idiopathic Pulmonary FibrosisR01HL143011 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI CLEVELAND, ZACKARY I · 2019 to 2023
$3.7M
A Phase III Trial to Validate HP 129Xe MRI as a Functional Pulmonary Biomarker in Pediatric Lung DiseaseR44HL123299 · NHLBI · POLAREAN, INC. · PI EMAMI, KIARASH · 2017 to 2019
$3.0M
Early detection of regional BOS in BMT patients using UTE and 129Xe MRIR00HL138255 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI WALKUP, LAURA LEE · 2020 to 2022
$747k
Early detection of regional BOS in BMT patients using UTE and 129Xe MRIK99HL138255 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI WALKUP, LAURA LEE · 2017 to 2018
$222k
NHLBI NIH HHS K99 HL138255NHLBI NIH HHS R01 HL131012NHLBI NIH HHS R01 HL143011NHLBI NIH HHS R44 HL123299NHLBI NIH HHS T32 HL007752
6 · The paper itself

Abstract

backgroundTwo functional measurements (multiple breath washout [MBW] and hyperpolarized

methodsSpirometry, MBW,

resultsMBW,

conclusionsMBW,

Indexed as

SpirometryChildCystic FibrosisFemaleHumansMagnetic Resonance ImagingMaleProspective StudiesSensitivity and SpecificityXenon IsotopesXenon IsotopesFunctionMRIMultiple breath washoutSpirometryStructureXenon

Identifiers

PMID33288474
PMCPMC8175447
OpenAlexW3108167951

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.