Evidence map›Paper›PMID 33288260›Full record

ArticleThe Science of the total environment2021

Association of low blood arsenic exposure with level of malondialdehyde among Chinese adults aged 65 and older.

Qiyue Tan, Yuebin Lv, Feng Zhao, Jinhui Zhou, Yang Yang, Yingchun Liu, Mingyuan Zhang, Feng Lu, Yuan Wei, Xin Chen and 12 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Science of the total environment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Arsenic, mercury, manganese, and lead exposure in Mexican adults aged 50 and older.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 5 institutions in 3 countries.

Qiyue TanChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; School of Public Health, Jilin University, Changchun, Jilin, China.
Yuebin LvChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Feng ZhaoChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Jinhui ZhouChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Yang YangThe University of Queensland Diamantina Institute, University of Queensland, Queensland, Australia.
Yingchun LiuChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Mingyuan ZhangChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; School of Public Health, Jilin University, Changchun, Jilin, China.
Feng LuBeijing Municipal Health Commission Information Center, (Beijing Municipal Health Commission Policy Research Center), Beijing 100034, China.
Yuan WeiChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; School of Public Health, Jilin University, Changchun, Jilin, China.
Xin ChenChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; School of Public Health, Jilin University, Changchun, Jilin, China.
Ruizhi ZhangSchool of Public Health, Jilin University, Changchun, Jilin, China.
Chen ChenChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Bing WuChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
Xiaochang ZhangChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Chengcheng LiChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Hongyuan HuangSchool of Public Health, Jilin University, Changchun, Jilin, China.
Junfang CaiChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Zhaojin CaoChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Di YuThe University of Queensland Diamantina Institute, University of Queensland, Queensland, Australia.
John S JiEnvironmental Research Center, Duke Kunshan University, Kunshan, Jiangsu, China; Nicholas School of the Environment, Duke University, Durham, NC, USA.
Shuhua ZhaoSchool of Public Health, Jilin University, Changchun, Jilin, China.
Xiaoming ShiChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China. Electronic address: shixm@chinacdc.cn.
Chinese Center For Disease Control and Prevention · CNJilin University · CNUniversity of Queensland · AUBeijing Municipal Education Commission · CNDuke University · US

Funding

THE RANGE OF MALE-FEMALE MORTALITY DIFFERENCESP01AG031719 · NIA · DUKE UNIVERSITY · PI CHRISTENSEN, KAARE · 2009 to 2020
$10.2M
NIA NIH HHS P01 AG031719
6 · The paper itself

Abstract

High environmental arsenic exposure can increase chronic oxidative stress in experimental studies and in occupational epidemiology studies. Many regulatory agencies have put forth arsenic exposure limits, it is still unclear that whether low environmental arsenic exposure was associated with adverse health outcome in general population. This study aimed to explore the association of low blood arsenic with malondialdehyde in community-dwelling older adults. We used a cross-sectional study of 2384 older adult individuals aged ≥65 years (mean age: 85 years) from the Healthy Aging and Biomarkers Cohort Study in 2017. The median blood arsenic level was 1.41 μg/L. High oxidative stress was categorized according to the 95th percentile of MDA levels (7.47 nmol/mL). Restricted cubic spline models showed that blood arsenic levels were positively associated with malondialdehyde levels (P < 0.01); and the risk of high oxidative stress was no longer significantly increased when blood arsenic level up to 8.74 μg/L. After adjusting for potential confounders, the odds ratios of high oxidative stress for the second, third, and fourth quartiles of blood arsenic were 2.35 (1.11-4.96), 3.87 (1.90-7.91), and 4.18 (2.00-8.72) (P

Indexed as

ArsenicAgedAged, 80 and overAsian PeopleCohort StudiesCross-Sectional StudiesEnvironmental ExposureHumansMalondialdehydeArsenicMalondialdehydeBlood arsenicMalondialdehydeOlder adultsRestricted cubic spline

Identifiers

PMID33288260
PMCPMC7897719
OpenAlexW3100501193

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.