Evidence map›Paper›PMID 33288208›Full record

ArticleBritish journal of anaesthesia2021

Potential for personalised application of inhaled nitric oxide in COVID-19 pneumonia.

Benjamin Garfield, Charles McFadyen, Charlotte Briar, Caroline Bleakley, Aikaterini Vlachou, Melissa Baldwin, Nick Lees, Susanna Price, Stephane Ledot, Colm McCabe and 3 more

2 registry-linked trialsOpen access · bronzeAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in British journal of anaesthesia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04290871 phase2withdrawnnot on this mapstarted 2023, after this paper: background citation

Nitric Oxide Gas Inhalation Therapy for Severe Acute Respiratory Syndrome Due to COVID-19.

TypeinterventionalSponsorXijing HospitalRan2023 to 2024Enrolled0ConditionsCoronavirus Covid-19 Infection Variant Omicron, SARS (Severe Acute Respiratory Syndrome)ArmsNitric Oxide Gas, The delivery system will be set up anyway without study gas administration
NCT05721144 phase2completednot on this mapstarted 2023, after this paper: background citation

Inhaled NO ReDuce postoperatIve pulmoNAry complicATions in patiEnts With Recent COVID-19 Infection

TypeinterventionalSponsorXijing HospitalRan2023 to 2024Enrolled660ConditionsNitric Oxide, COVID-19, Surgery, Postoperative ComplicationsArmsNitric Oxide Gas
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
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  10. Article
  11. Nitric oxide mediated hypoxia dynamics in COVID-19.Nitric oxide : biology and chemistry · 2023
    Review
  12. Review
  13. Observational
  14. Review
  15. Review
  16. Utility of NO and HNitric oxide : biology and chemistry · 2022
    Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 3 countries.

Benjamin GarfieldAdult Intensive Care Unit, Royal Brompton Hospital, London, UK; National Heart and Lung Institute, Imperial College London, London, UK.
Charles McFadyenAdult Intensive Care Unit, Royal Brompton Hospital, London, UK.
Charlotte BriarAdult Intensive Care Unit, Royal Brompton Hospital, London, UK.
Caroline BleakleyAdult Intensive Care Unit, Royal Brompton Hospital, London, UK.
Aikaterini VlachouAdult Intensive Care Unit, Royal Brompton Hospital, London, UK.
Melissa BaldwinAdult Intensive Care Unit, Royal Brompton Hospital, London, UK.
Nick LeesAdult Intensive Care Unit, Harefield Hospital, Harefield, UK.
Susanna PriceAdult Intensive Care Unit, Royal Brompton Hospital, London, UK; National Heart and Lung Institute, Imperial College London, London, UK.
Stephane LedotAdult Intensive Care Unit, Royal Brompton Hospital, London, UK.
Colm McCabeNational Heart and Lung Institute, Imperial College London, London, UK; National Pulmonary Hypertension Service, Royal Brompton Hospital, UK.
S John WortNational Heart and Lung Institute, Imperial College London, London, UK; National Pulmonary Hypertension Service, Royal Brompton Hospital, UK.
Brijesh V PatelAdult Intensive Care Unit, Royal Brompton Hospital, London, UK; Anaesthetics, Pain Medicine and Intensive Care, Surgery and Cancer, Imperial College London, UK.
Laura C PriceNational Heart and Lung Institute, Imperial College London, London, UK; National Pulmonary Hypertension Service, Royal Brompton Hospital, UK. Electronic address: laura.price@rbht.nhs.uk.
Royal Brompton Hospital · GBHarefield Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Administration, InhalationCOVID-19HemodynamicsHumansHypercapniaHypoxiaNitric OxideRespiratory Distress SyndromeSARS-CoV-2Treatment OutcomeVasodilator AgentsNitric OxideVasodilator AgentsARDSCOVID-19inhaled nitric oxidepulmonary hypertensionright ventricular dysfunction

Identifiers

PMID33288208
PMCPMC7666572
OpenAlexW3105814512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.