Evidence map›Paper›PMID 33287959›Full record

ArticleeLife2020

Respiratory tissue-associated commensal bacteria offer therapeutic potential against pneumococcal colonization.

Soner Yildiz, João P Pereira Bonifacio Lopes, Matthieu Bergé, Víctor González-Ruiz, Damian Baud, Joachim Kloehn, Inês Boal-Carvalho, Olivier P Schaeren, Michael Schotsaert, Lucy J Hathaway and 5 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 38 citations in OpenAlex.

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  18. Frontiers in microbiology · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Soner Yildiz *Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
João P Pereira Bonifacio Lopes *Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Matthieu BergéDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID 0000-0002-0910-6114
Víctor González-RuizAnalytical Sciences, School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland.
Damian BaudDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Joachim KloehnDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Inês Boal-CarvalhoDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Olivier P SchaerenInstitute for Infectious Disease (IFIK), University of Bern, Bern, Switzerland.
Michael SchotsaertDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, United States.
Lucy J HathawayInstitute for Infectious Disease (IFIK), University of Bern, Bern, Switzerland.
Serge RudazAnalytical Sciences, School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland.
Patrick H ViollierDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID 0000-0002-5249-9910
Siegfried HapfelmeierInstitute for Infectious Disease (IFIK), University of Bern, Bern, Switzerland.
Patrice FrancoisDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Mirco SchmolkeDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID 0000-0002-2491-3029
University of Geneva · CHUniversity of Bern · CHIcahn School of Medicine at Mount Sinai · US

Funding

H2020 European Research Council 695596Swiss National Science Foundation 155959Swiss National Science Foundation 162808Swiss National Science Foundation 169791Swiss National Science Foundation 182475Swiss National Science Foundation 182576
6 · The paper itself

Abstract

Under eubiotic conditions commensal microbes are known to provide a competitive barrier against invading bacterial pathogens in the intestinal tract, on the skin or on the vaginal mucosa. Here, we evaluate the role of lung microbiota in Pneumococcus colonization of the lungs. In eubiosis, the lungs of mice were dominantly colonized by

Indexed as

AnimalsCarrier StateCulture Media, ConditionedFemaleLactic AcidLactobacillusLungMiceMice, Inbred C57BLStreptococcus pneumoniaeSymbiosisCulture Media, ConditionedLactic Acidcolonization resistanceinfectious diseaseInfluenza A viruslactobacillus murinuslung microbiomemicrobiologymouseprobioticsStreptococcus pneumoniaevirus

Identifiers

PMID33287959
PMCPMC7723408
OpenAlexW3111327226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.