ArticleCritical care (London, England)2020
Risk factors and events in the adult intensive care unit associated with pain as self-reported at the end of the intensive care unit stay.
Article in Critical care (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02442934 (A Multicomponent Intervention to Reduce Perceived Discomforts in Critically Ill Patients), which is not on this map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Multicomponent Intervention to Reduce Perceived Discomforts in Critically Ill Patients: a Randomized Controlled Trial
Who cites it
8 citing papers in PubMed, 23 citations in OpenAlex.
- Incidence and Associated Factors for Chronic Pain After ICU Discharge: A Prospective Study.Nursing in critical care · 2026Article
- Early Markers of Systemic Inflammation are not Related to Pain Burden After Aneurysmal Subarachnoid Hemorrhage: A Multicenter Observational Study.Neurocritical care · 2026Observational
- Trajectories of emotional and physical distress during ICU stay and their association with clinical factors and cognitive status at discharge.Scientific reports · 2026Observational
- Knowledge, attitudes, and practices of ICU nurses regarding daily sedation interruption: a cross-sectional study.Frontiers in medicine · 2026Article
- Psychological intervention based on social cognitive theory: Treating pain, anxiety, and depression in perioperative patients.World journal of psychiatry · 2024Article
- Self-reported symptoms experienced by intensive care unit patients: a prospective observational multicenter study.Intensive care medicine · 2023Observational
- Are we ready to manage an opioid epidemic in the intensive care unit?Anaesthesiology intensive therapy · 2022Review
- Factors Associated With Deep Sedation Practice in Mechanically Ventilated Patients: AFrontiers in medicine · 2022Article
Corrections and comments
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Authors and funding
32 authors at 20 institutions in 1 country.
Funding
Abstract
backgroundThe short-term and long-term consequences of the most frequent painful procedures performed in the ICU are unclear. This study aimed to identify the risk factors associated with pain-related discomfort perceived by critically ill patients during the whole ICU stay as self-reported by patients at the end of their ICU stay.
methodsThe study involved 34 ICUs. Adult patients who survived an ICU stay of 3 calendar days or more were eligible for inclusion. Discomforts, including the pain-related discomfort, were assessed using the French 18-item questionnaire on discomfort in ICU patients, the "Inconforts des Patients de REAnimation" (IPREA). Patients scored each item from 0 (minimal discomfort) to 10 (maximal discomfort). Associations between patient characteristics at ICU admission, life support therapies and main potentially painful procedures performed during the ICU stay and pain-related discomfort scores assessed at the end of the ICU stay were analyzed.
resultsPatients with complete IPREA questionnaires (n = 2130) were included. The median pain-related discomfort score was 3 (IQR 0-5). From the univariate analysis, pain-related discomfort scores were negatively correlated with age and positively correlated with ICU stay duration; surgical patients reported significant higher pain-related discomfort scores than medical patients; chest drain insertion, chest drain removal, use of bladder catheter, central venous catheter (CVC) insertion, complex dressing change, and intra-hospital transport were associated with pain-related discomfort scores. From the multivariate analyses using generalized estimating equations models, only age, chest drain removal, use of a bladder catheter, CVC insertion, and intra-hospital transport were the main risk factors associated with pain-related discomfort scores.
conclusionPatients who underwent chest drain removal, bladder catheter, CVC insertion, and intra-hospital transport during their ICU stay reported higher pain-related discomfort scores (with respect to the whole ICU stay and assessed at the end of their ICU stay) than patients who did not experience these events. This study may pave the way for further targeted studies aiming at investigating a causal link between these common procedures in the ICU and adult critically ill patients' perceptions of their ICU stay regarding recalled pain.
trial registrationClinicaltrials.gov Identifier NCT02442934, retrospectively registered on May 13, 2015.
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