Evidence map›Paper›PMID 33287743›Full record

ArticleBMC ophthalmology2020

Accelerated corneal endothelial cell loss in two patients with granulomatosis with polyangiitis following phacoemulsification.

Fang-Chi Hsiao, Hung-Ta Chen, Kuan-Jen Chen, Yi-Jen Hsueh, Yaa-Jyuhn James Meir, Tsai-Te Lu, Chao-Min Cheng, Wei-Chi Wu, Hung-Chi Chen

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Fang-Chi HsiaoDepartment of Ophthalmology, Chang Gung Memorial Hospital, No. 5, Fuxing Street, Guishan District, Linkou, Taoyuan, 33305, Taiwan.
Hung-Ta ChenDepartment of Internal Medicine, Taipei City Hospital- Heping Branch, Taipei, Taiwan.
Kuan-Jen ChenDepartment of Ophthalmology, Chang Gung Memorial Hospital, No. 5, Fuxing Street, Guishan District, Linkou, Taoyuan, 33305, Taiwan.
Yi-Jen HsuehDepartment of Ophthalmology, Chang Gung Memorial Hospital, No. 5, Fuxing Street, Guishan District, Linkou, Taoyuan, 33305, Taiwan.
Yaa-Jyuhn James MeirDepartment of Biomedical Sciences, Chang Gung University College of Medicine, Taiyuan, Taiwan.
Tsai-Te LuInstitute of Biomedical Engineering, National Tsing Hua University, Hsinchu, Taiwan.
Chao-Min ChengInstitute of Biomedical Engineering, National Tsing Hua University, Hsinchu, Taiwan.
Wei-Chi WuDepartment of Ophthalmology, Chang Gung Memorial Hospital, No. 5, Fuxing Street, Guishan District, Linkou, Taoyuan, 33305, Taiwan.
Hung-Chi ChenDepartment of Ophthalmology, Chang Gung Memorial Hospital, No. 5, Fuxing Street, Guishan District, Linkou, Taoyuan, 33305, Taiwan. mr3756@cgmh.org.tw.ORCID http://orcid.org/0000-0002-1117-7878
Chang Gung University · TWNational Tsing Hua University · TW

Funding

Chang Gung Memorial Hospital, Linkou CMRPG3G0021-3 & CMRPG3G0031-3Ministry of Science and Technology, Taiwan MOST 107-2314-B-182A-088-MY3
6 · The paper itself

Abstract

backgroundGenerally, the loss rate of human endothelial cells (HCEC) in routine cataract surgery is 8.5%. When the corneal endothelial cells density (ECD) drops, the HCEC may decompensate to keep cornea dehydration which leads to corneal edema. Granulomatosis with polyangiitis (GPA) is an uncommon autoimmune disease involving multiple organs including eyes such as conjunctivitis, scleritis, uveitis, and corneal ulcer. In this study, we report two cases of GPA whose corneal ECD decreased significantly after phacoemulsification cataract surgery. CASE PRESENTATION: In the first case of 69-year-old male with GPA, the ECD dropped 39.6% (OD) four months after phacoemulsification and 38.1% (OS) six months postoperatively respectively. At the final follow-up, the residual ECD was only 55% in the right eye in the 49

conclusionExtensive preoperative ophthalmic evaluation and meticulous postoperative inflammation control should be applied to prevent severe loss of HCEC in GPA patients.

Indexed as

Granulomatosis with PolyangiitisPhacoemulsificationAgedCell CountCorneal Endothelial Cell LossEndothelial CellsEndothelium, CornealFemaleHumansLens Implantation, IntraocularMaleMiddle AgedCataractCornealEndothelial cell density (ECD)Granulomatosis with polyangiitisPhacoemulsification

Identifiers

PMID33287743
PMCPMC7720459
OpenAlexW3111174313

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.