Evidence map›Paper›PMID 33287730›Full record

ArticleBMC nephrology2020

Safely reducing haemodialysis frequency during the COVID-19 pandemic.

Michelle Da Silva Lodge, Thilini Abeygunaratne, Helen Alderson, Ibrahim Ali, Nina Brown, Constantina Chrysochou, Rosie Donne, Ibi Erekosima, Philip Evans, Emma Flanagan and 19 more

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Impact of incremental initiation of haemodialysis on mortality: a systematic review and meta-analysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Pooled it
  2. Article
  3. Article
  4. Disasters and kidney care: pitfalls and solutions.Nature reviews. Nephrology · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 1 institution in 1 country.

Michelle Da Silva LodgeDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Thilini AbeygunaratneDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Helen AldersonDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Ibrahim AliDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Nina BrownDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Constantina ChrysochouDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Rosie DonneDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Ibi ErekosimaDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Philip EvansDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Emma FlanaganDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Simon GrayDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Darren GreenDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Janet HegartyDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Audrey HydeDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Philip A KalraDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Elizabeth LamertonDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
David LewisDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Rachel MiddletonDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
David NewDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Robert NipahDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Donal O'DonoghueDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Edmond O'RiordanDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Dimitrios PoulikakosDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Francesco RainoneDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Maharajan RamanDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
James RitchieDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Smeeta SinhaDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
Grahame WoodDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK.
J TollittDepartment of Renal Medicine, Salford Royal NHS Trust, Stott Lane, Salford, M68HD, UK. James.Tollitt@srft.nhs.uk.ORCID 0000-0002-9825-701X
Salford Royal NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients undergoing haemodialysis (HD) are at higher risk of developing worse outcomes if they contract COVID-19. In our renal service we reduced HD frequency from thrice to twice-weekly in selected patients with the primary aim of reducing COVID 19 exposure and transmission between HD patients.

methodsDialysis unit nephrologists identified 166 suitable patients (38.4% of our HD population) to temporarily convert to twice-weekly haemodialysis immediately prior to the peak of the COVID-19 pandemic in our area. Changes in pre-dialysis weight, systolic blood pressure (SBP) and biochemistry were recorded weekly throughout the 4-week project. Hyperkalaemic patients (serum potassium > 6.0 mmol/L) were treated with a potassium binder, sodium bicarbonate and received responsive dietary advice.

resultsThere were 12 deaths (5 due to COVID-19) in the HD population, 6 of which were in the twice weekly HD group; no deaths were definitively associated with change of dialysis protocol. A further 19 patients were either hospitalised and/or developed COVID-19 and thus transferred back to thrice weekly dialysis as per protocol. 113 (68.1%) were still receiving twice-weekly HD by the end of the 4-week project. Indications for transfer back to thrice weekly were; fluid overload (19), persistent hyperkalaemia (4), patient request (4) and compliance (1). There were statistically significant increases in SBP and pre-dialysis potassium during the project.

conclusionsShort term conversion of a large but selected HD population to twice-weekly dialysis sessions was possible and safe. This approach could help mitigate COVID-19 transmission amongst dialysis patients in centres with similar organisational pressures.

Indexed as

Appointments and SchedulesPandemicsSARS-CoV-2AgedAmbulatory Care FacilitiesBlood PressureBody WeightComorbidityCOVID-19EnglandFemaleHumansHyperkalemiaKidney Failure, ChronicMaleMiddle AgedPotassiumCoronavirusCOVID-19HaemodialysisMortalitySARS-CoV-2Twice weekly

Identifiers

PMID33287730
PMCPMC7720264
OpenAlexW3103650124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.