Evidence map›Paper›PMID 33287719›Full record

ArticleBMC nephrology2020

Impacts of dialysis adequacy and intradialytic hypotension on changes in dialysis recovery time.

Murilo Guedes, Roberto Pecoits-Filho, Juliana El Ghoz Leme, Yue Jiao, Jochen G Raimann, Yuedong Wang, Peter Kotanko, Thyago Proença de Moraes, Ravi Thadhani, Franklin W Maddux and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Observational
  3. Article
  4. Review
  5. Article
  6. Post-dialysis recovery time in ESRD patients receiving more frequent hemodialysis in skilled nursing facilities.Hemodialysis international. International Symposium on Home Hemodialysis · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Murilo GuedesSchool of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil.
Roberto Pecoits-FilhoSchool of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil.
Juliana El Ghoz LemeSchool of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil.
Yue JiaoGlobal Medical Office, Fresenius Medical Care, 920 Winter Street, Waltham, MA, 02451, USA.
Jochen G RaimannResearch Division, Renal Research Institute, New York, NY, USA.
Yuedong WangUniversity of California Santa Barbara, Santa Barbara, CA, USA.
Peter KotankoResearch Division, Renal Research Institute, New York, NY, USA.
Thyago Proença de MoraesSchool of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil.
Ravi ThadhaniPartners HealthCare, Boston, MA, USA.
Franklin W MadduxGlobal Medical Office, Fresenius Medical Care, 920 Winter Street, Waltham, MA, 02451, USA.
Len A UsvyatGlobal Medical Office, Fresenius Medical Care, 920 Winter Street, Waltham, MA, 02451, USA.
John W LarkinSchool of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil. john.larkin@fmc-na.com.ORCID 0000-0001-8873-8971
Pontifícia Universidade Católica do Paraná · BRFresenius Medical Care (United States) · USRenal Research Institute · USMass General Brigham · USUniversity of California, Santa Barbara · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDialysis recovery time (DRT) surveys capture the perceived time after HD to return to performing regular activities. Prior studies suggest the majority of HD patients report a DRT > 2 h. However, the profiles of and modifiable dialysis practices associated with changes in DRT relative to the start of dialysis are unknown. We hypothesized hemodialysis (HD) dose and rates of intradialytic hypotension (IDH) would associate with changes in DRT in the first years after initiating dialysis.

methodsWe analyzed data from adult HD patients who responded to a DRT survey ≤180 days from first date of dialysis (FDD) during 2014 to 2017. DRT survey was administered with annual KDQOL survey. DRT survey asks: "How long does it take you to be able to return to your normal activities after your dialysis treatment?" Answers are: < 0.5, 0.5-to-1, 1-to-2, 2-to-4, or > 4 h. An adjusted logistic regression model computed odds ratio for a change to a longer DRT (increase above DRT > 2 h) in reference to a change to a shorter DRT (decrease below DRT < 2 h, or from DRT > 4 h). Changes in DRT were calculated from incident (≤180 days FDD) to first prevalent (> 365-to- ≤ 545 days FDD) and second prevalent (> 730-to- ≤ 910 days FDD) years.

resultsAmong 98,616 incident HD patients (age 62.6 ± 14.4 years, 57.8% male) who responded to DRT survey, a higher spKt/V in the incident period was associated with 13.5% (OR = 0.865; 95%CI 0.801-to-0.935) lower risk of a change to a longer DRT in the first-prevalent year. A higher number of HD treatments with IDH episodes per month in the incident period was associated with a 0.8% (OR = 1.008; 95%CI 1.001-to-1.015) and 1.6% (OR = 1.016; 95%CI 1.006-to-1.027) higher probability of a change to a longer DRT in the first- and second-prevalent years, respectively. Consistently, an increased in incidence of IDH episodes/months was associated to a change to a longer DRT over time.

conclusionsIncident patients who had higher spKt/V and less sessions with IDH episodes had a lower likelihood of changing to a longer DRT in first year of HD. Dose optimization strategies with cardiac stability in fluid removal should be tested.

Indexed as

Recovery of FunctionAgedBody Mass IndexFemaleHumansHypotensionKidney Failure, ChronicLogistic ModelsMaleMiddle AgedRenal DialysisSex FactorsSurveys and QuestionnairesTime FactorsAdequacyDialysis recovery timeHealth related quality of lifeIntradialytic hypotensionPatient reported outcomes

Identifiers

PMID33287719
PMCPMC7720452
OpenAlexW3110972273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.