Evidence map›Paper›PMID 33287648›Full record

ArticleTechnology in cancer research & treatment

CTNNB1 Knockdown Inhibits Cell Proliferation and Aldosterone Secretion Through Inhibiting Wnt/β-Catenin Signaling in H295R Cells.

Tingting Zhou, Pengwei Luo, Liang Wang, Shiwei Yang, Shiyuan Qin, Zhitao Wei, Jiwen Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Cardiovascular diagnosis and therapy · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tingting ZhouDepartment of Urology, The General Hospital of Western Theater Command PLA, Chengdu, China.ORCID 0000-0001-9568-4094
Pengwei LuoDepartment of Urology, The General Hospital of Western Theater Command PLA, Chengdu, China.
Liang WangDepartment of Urology, The General Hospital of Western Theater Command PLA, Chengdu, China.
Shiwei YangDepartment of Urology, The General Hospital of Western Theater Command PLA, Chengdu, China.
Shiyuan QinDepartment of Urology, The General Hospital of Western Theater Command PLA, Chengdu, China.
Zhitao WeiDepartment of Urology, The First Affiliated Hospital of Chengdu Medical College.
Jiwen LiuDepartment of Urology, The General Hospital of Western Theater Command PLA, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aldosterone-producing adenomas (APA) is one of the causative factors of primary aldosteronism. Previous studies have suggested that there are somatic

Indexed as

Wnt Signaling PathwayAdrenal Cortex NeoplasmsAldosteronebeta CateninCell Line, TumorCells, CulturedCell SurvivalCyclin D1Gene ExpressionGene Knockdown TechniquesHumansHyperaldosteronismAldosteronebeta CateninCCND1 protein, humanCTNNB1 protein, humanCyclin D1aldosterone-producing adenomasaldosterone secretionCTNNBH295 R cellWnt/β-catenin signaling pathway

Identifiers

PMID33287648
PMCPMC7727057

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.