ArticleAging & mental health2021
A longitudinal analysis of the relationships between depression, fatigue, and pain in patients with heart failure.
Article in Aging & mental health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 18 citations in OpenAlex.
- A secondary analysis of how changes in pain interference relate to changes in health-related quality of life and physical function in heart failure.Heart & lung : the journal of critical careTrial
- Healthcare-related social determinants of health are associated with pain severity among adults with comorbid heart failure and chronic pain.BMC health services research · 2026Article
- From childhood shadows to adult aches: a prospective cohort study on adverse childhood experiences, depressive symptoms, and incident arthritis in middle-aged and older Chinese adults.European journal of medical research · 2025Article
- Network Analysis of Sexual Well-Being in Women with Heart Failure: The Psychocardiological Perspective.Healthcare (Basel, Switzerland) · 2024Article
- Pain relief and associated factors: a cross-sectional observational web-based study in a Quebec cohort of persons living with chronic pain.Frontiers in pain research (Lausanne, Switzerland) · 2024Article
- Association between persistent musculoskeletal pain and incident sarcopenia in China: the mediating effect of depressive symptoms.Frontiers in public health · 2024Article
- New perspective on fatigue in hemodialysis patients with preserved ejection fraction: diastolic dysfunction : Fatigue and diastolic dysfunction.The international journal of cardiovascular imaging · 2022Article
- Palliative Care for People Living With Heart Disease-Does Sex Make a Difference?Frontiers in cardiovascular medicine · 2021Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesDepression, pain, and fatigue are common and bothersome symptoms in heart failure, a serious illness in older adults. Understanding longitudinal pathways among depression, pain, and fatigue in heart failure could inform treatment and improve quality of life.
methodsWe completed secondary, longitudinal data analyses of a sample of older adults with heart failure (baseline
resultsDepressive symptoms were associated with new onset of pain symptoms; however, this association was mediated by fatigue. Pain was not associated with new depression or fatigue symptoms in this sample. DISCUSSION: In patients with heart-failure, worsening pain symptoms appear to be directly related to levels of depression and fatigue. These findings demonstrate that depression and fatigue may be key to reducing pain symptoms in this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.