ReviewCancers2020
Long-Term Neurodevelopmental Outcome of Children after in Utero Exposure to Chemotherapy.
Review in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Colorectal Cancer Treatment During Pregnancy.Journal of the advanced practitioner in oncology · 2026Article
- Motor development in toddlers prenatally exposed to maternal cancer treatment: a national cohort study in the Netherlands.EClinicalMedicine · 2026Article
- Review
- Review
- The impact ofHuman reproduction open · 2025Review
- Influence of cancer in pregnancy on obstetric and neonatal outcomes: an observational retrospective cohort study.Journal of gynecologic oncology · 2024Observational
- Approaching cancer during pregnancy.Nature reviews. Cancer · 2024Article
- Successful pregnancy after cyclophosphamide therapy for systemic lupus erythematosus: a case report.Annals of medicine and surgery (2012) · 2024Article
- Neonatal outcomes and follow-up of children born to women with pregnancy-associated cancer: a prospective observational study.BMC pregnancy and childbirth · 2024Observational
- Cancer and Pregnancy in the Post-Roe v. Wade Era: A Comprehensive Review.Current oncology (Toronto, Ont.) · 2023Review
- The Effect and Safety of Olanzapine on Nausea and Vomiting in Children Receiving Moderately Emetogenic Chemotherapy.Advanced biomedical research · 2023Article
- Germline mutations in a clinic-based series of pregnancy associated breast cancer patients.BMC cancer · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pregnancy-related cancer management represents a real challenge for both the patients and the physicians. The long-term neurodevelopmental outcome of children in utero exposed to chemotherapeutic agents has only recently been addressed. This review aims to systematically integrate and highlight all existing data from the literature regarding the effect of prenatal exposure to chemotherapy on fetal brain growth and child development. All eligible studies are based on validated neurodevelopmental testing scales (e.g., Bayley Scales of Infant Development, Wechsler Preschool and Primary Scale of Intelligence) and/or well-defined questionnaires. Our systematic review including 17 studies demonstrates that no major consequences on the neurodevelopment of children after in utero exposure to anti-cancer drugs have been reported; nevertheless, longer and more thorough follow-up with large-scale multicenter prospective studies is certainly required in order to draw firm conclusions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.