Evidence map›Paper›PMID 33287259›Full record

ReviewPathogens (Basel, Switzerland)2020

Anti-Influenza Strategies Based on Nanoparticle Applications.

Klaudia Wieczorek, Barbara Szutkowska, Elzbieta Kierzek

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
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  8. Article
  9. Review
  10. Silver nanoparticles as a potential treatment against SARS-CoV-2: A review.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2021
    Review
  11. The Crossroads between Host Copper Metabolism and Influenza Infection.International journal of molecular sciences · 2021
    Review
  12. How nano can fight the virus.Nature materials · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Klaudia WieczorekInstitute of Bioorganic Chemistry, Polish Academy of Sciences, 61-704 Poznan, Poland.ORCID 0000-0001-9084-4220
Barbara SzutkowskaInstitute of Bioorganic Chemistry, Polish Academy of Sciences, 61-704 Poznan, Poland.
Elzbieta KierzekInstitute of Bioorganic Chemistry, Polish Academy of Sciences, 61-704 Poznan, Poland.
Institute of Bioorganic Chemistry, Polish Academy of Sciences · PL

Funding

National Science Centre UMO-2020/01/0/NZ6/00137
6 · The paper itself

Abstract

Influenza virus has the potential for being one of the deadliest viruses, as we know from the pandemic's history. The influenza virus, with a constantly mutating genome, is becoming resistant to existing antiviral drugs and vaccines. For that reason, there is an urgent need for developing new therapeutics and therapies. Despite the fact that a new generation of universal vaccines or anti-influenza drugs are being developed, the perfect remedy has still not been found. In this review, various strategies for using nanoparticles (NPs) to defeat influenza virus infections are presented. Several categories of NP applications are highlighted: NPs as immuno-inducing vaccines, NPs used in gene silencing approaches, bare NPs influencing influenza virus life cycle and the use of NPs for drug delivery. This rapidly growing field of anti-influenza methods based on nanotechnology is very promising. Although profound research must be conducted to fully understand and control the potential side effects of the new generation of antivirals, the presented and discussed studies show that nanotechnology methods can effectively induce the immune responses or inhibit influenza virus activity both in vitro and in vivo. Moreover, with its variety of modification possibilities, nanotechnology has great potential for applications and may be helpful not only in anti-influenza but also in the general antiviral approaches.

Indexed as

antisense strategiesdeliveryinfluenzainfluenza vaccineinfluenza virusinhibitionnanoparticlesnanotechnologyresistance

Identifiers

PMID33287259
PMCPMC7761763
OpenAlexW3109034087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.